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金黄色葡萄球菌菌血症的抗血小板治疗:过去的时光并非一无是处?

Antiplatelet Therapy in Staphylococcus aureus Bacteremia: No Time Like the Past?

机构信息

Department of Medicine, Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina, USA.

Duke Clinical Research Institute, Durham, North Carolina, USA.

出版信息

Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0036522. doi: 10.1128/aac.00365-22. Epub 2022 May 10.

Abstract

In this invited commentary, we reflect on the accompanying study by A. R. Caffrey, H. J. Appaneal, K. L. LaPlante, V. V. Lopes, et al. (Antimicrob Agents Chemother 66:e02117-21, 2022, https://doi.org/10.1128/aac.02117-21), which analyzed the impact of clopidogrel use on clinical outcomes in Staphylococcus aureus bacteremia.

摘要

在这篇特邀评论中,我们对 A. R. Caffrey、H. J. Appaneal、K. L. LaPlante、V. V. Lopes 等人的伴随研究进行了反思(Antimicrob Agents Chemother 66:e02117-21,2022,https://doi.org/10.1128/aac.02117-21),该研究分析了氯吡格雷在金黄色葡萄球菌菌血症中的使用对临床结果的影响。

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本文引用的文献

1
Impact of Clopidogrel on Clinical Outcomes in Patients with Staphylococcus aureus Bacteremia: a National Retrospective Cohort Study.
Antimicrob Agents Chemother. 2022 Jun 21;66(6):e0211721. doi: 10.1128/aac.02117-21. Epub 2022 Apr 13.
2
Ticagrelor Increases Platelet-Mediated Staphylococcus aureus Killing, Resulting in Clearance of Bacteremia.
J Infect Dis. 2021 Nov 16;224(9):1566-1569. doi: 10.1093/infdis/jiab146.
3
Risk of infectious events in acute myocardial infarction patients treated with ticagrelor or clopidogrel.
Eur J Intern Med. 2021 Mar;85:121-123. doi: 10.1016/j.ejim.2020.10.016. Epub 2020 Nov 14.
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Ticagrelor and the risk of Staphylococcus aureus bacteraemia and other infections.
Eur Heart J Cardiovasc Pharmacother. 2022 Jan 5;8(1):13-19. doi: 10.1093/ehjcvp/pvaa099.
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Effect of Ticagrelor on Reducing the Risk of Gram-Positive Infections in Patients With Acute Coronary Syndrome.
Am J Cardiol. 2020 Sep 1;130:56-63. doi: 10.1016/j.amjcard.2020.06.016. Epub 2020 Jun 17.

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