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美国肺癌肺叶切除术中补充区域麻醉的应用:一项回顾性研究。

Utilization of Supplemental Regional Anesthesia in Lobectomy for Lung Cancer in the United States: A Retrospective Study.

作者信息

Alwatari Yahya, Vudatha Vignesh, Scheese Daniel, Rustom Salem, Ayalew Dawit, Sevdalis Athanasios E, Julliard Walker, Shah Rachit D

机构信息

Department of Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA.

出版信息

J Chest Surg. 2022 Jun 5;55(3):225-232. doi: 10.5090/jcs.21.152.

Abstract

BACKGROUND

Pulmonary lobectomy is the standard of care for the treatment of early-stage non-small cell lung cancer. This study investigated the rate of utilization of supplemental anesthesia in patients undergoing video-assisted thoracoscopic surgery (VATS) or open lobectomy using a national database and assessed the effect of regional block (RB) on postoperative outcomes.

METHODS

Patients who underwent lobectomy for lung cancer between 2014-2019 were identified in the American College of Surgeons National Surgical Quality Improvement Program. The patients' primary mode of anesthesia and supplemental anesthesia were recorded. Preoperative characteristics and postoperative outcomes were compared between 2 surgical groups: those who underwent general anesthesia (GA) alone versus GA with RB. Multivariable regression analyses were performed on the outcomes of interest.

RESULTS

In total, 13,578 patients met the study criteria, with 87% undergoing GA and the remaining 13% receiving GA and RB. The use of neuraxial anesthesia decreased over the years, while RB use increased up to 20% in 2019. Age, body mass index, and preoperative comorbidities were comparable between groups. Patients who underwent VATS were more likely to receive RB than those who underwent thoracotomy. RB was most often utilized by thoracic surgeons. An adjusted analysis showed that RB use was associated with shorter hospital stays and a reduced likelihood of prolonged length of stay, but a higher rate of surgical site infections (SSIs).

CONCLUSION

In a large surgical database, there was underutilization of supplemental anesthesia in patients undergoing lobectomy for lung cancer. RB utilization was associated with a shorter length of hospital stay and an increase in SSI incidence.

摘要

背景

肺叶切除术是早期非小细胞肺癌治疗的标准术式。本研究利用全国性数据库调查了接受电视辅助胸腔镜手术(VATS)或开胸肺叶切除术患者的辅助麻醉使用率,并评估了区域阻滞(RB)对术后结局的影响。

方法

在美国外科医师学会国家外科质量改进计划中识别出2014年至2019年间接受肺癌肺叶切除术的患者。记录患者的主要麻醉方式和辅助麻醉情况。比较两个手术组的术前特征和术后结局:单纯接受全身麻醉(GA)的患者与接受GA联合RB的患者。对感兴趣的结局进行多变量回归分析。

结果

共有13578例患者符合研究标准,其中87%接受GA,其余13%接受GA联合RB。多年来,神经轴索麻醉的使用减少,而RB的使用在2019年增至20%。两组间年龄、体重指数和术前合并症具有可比性。接受VATS的患者比接受开胸手术的患者更有可能接受RB。RB最常由胸外科医生使用。校正分析显示,使用RB与住院时间缩短及住院时间延长可能性降低相关,但手术部位感染(SSI)发生率较高。

结论

在一个大型手术数据库中,接受肺癌肺叶切除术的患者辅助麻醉使用不足。RB的使用与住院时间缩短及SSI发生率增加相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2895/9178309/6f9dc8178ae4/jcs-55-3-225-f1.jpg

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