Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
BMC Prim Care. 2022 May 10;23(1):113. doi: 10.1186/s12875-022-01719-6.
Medication adherence among Psoriasis patients is often inadequate identified as a significant problem in Psoriasis symptoms management. Poor medication adherence could necessitate stronger and more expensive medications, which could place a significant burden on the healthcare system. Moreover, the importance of health literacy assessment as a factor influencing adherence in psoriasis patients cannot be overstated. This study aimed to evaluate the medication adherence level of Iranian Psoriasis patients and its relationship with the patients' health literacy level and demographic conditions.
This is a cross-sectional study among Iranian psoriasis patients conducted through a web-based questionnaire survey between 26 July 2020 and 5 January 2021 and a total of 575 samples were collected. The questionnaire consisted of 3 sections: First, demographic information and disease characteristics were evaluated. Second, the medication adherence was evaluated by using valid Morisky Medication Adherence Scale-8 (MMAS-8), and, finally, the health literacy was evaluated by using Health Literacy for Iranian Adults (HELIA). Data were analyzed using SPSS software, version 22 with descriptive statistics; Chi-square and Kruskal-Wallis tests. Stepwise multiple linear regression was also used to evaluate the impact of independent variables related on medication adherence score.
Results showed that the mean health literacy score in the study population was 74.3 ± 14.23, and the mean medication adherence score was 4.1 ± 2.18. Out of the total participants, 28.8% had high health literacy, 67.1% had adequate health literacy, and 4% had inadequate health literacy. The majority of the participants (70.7%) reported low adherence, while 24.1% reported moderate and 5.2% reported high adherence. The results of the Chi-square test showed a significant relationship between age, comorbidities, type of treatment, satisfaction with treatment, the experience of adverse effects, and health literacy with medication adherence (P < 0.05 for all). The final constructed model of stepwise multiple linear regression was highly statistically significant. The highest beta coefficient in the final model belonged to the total health literacy score.
Based on the results, medication adherence among Iranian psoriasis patients is low. Health literacy correlates most strongly with medication adherence and is the best variable to determine it. Improving the access to the internet and the ICTs to enhance the patients` health literacy along with developing the patient education approaches and techniques should be considered by health policymakers.
在银屑病患者的管理中，药物依从性往往不足，这被认为是一个严重的问题。药物依从性差可能需要更强效和更昂贵的药物，这可能会给医疗保健系统带来巨大负担。此外，健康素养评估作为影响银屑病患者依从性的一个因素的重要性怎么强调都不为过。本研究旨在评估伊朗银屑病患者的药物依从性水平及其与患者健康素养水平和人口统计学状况的关系。
这是一项在伊朗进行的银屑病患者的横断面研究，通过 2020 年 7 月 26 日至 2021 年 1 月 5 日的在线问卷调查进行，共收集了 575 个样本。问卷包括 3 个部分：第一部分评估人口统计学信息和疾病特征。第二部分通过有效的 Morisky 药物依从性量表-8（MMAS-8）评估药物依从性，最后，通过伊朗成年人健康素养量表（HELIA）评估健康素养。使用 SPSS 软件版本 22 进行数据的描述性统计分析；卡方检验和克鲁斯卡尔-沃利斯检验。还使用逐步多元线性回归来评估与药物依从性评分相关的独立变量的影响。
结果显示，研究人群的平均健康素养评分为 74.3±14.23，平均药物依从性评分为 4.1±2.18。在所有参与者中，28.8%的人具有较高的健康素养，67.1%的人具有足够的健康素养，4%的人具有不足的健康素养。大多数参与者（70.7%）报告低依从性，24.1%报告中等依从性，5.2%报告高依从性。卡方检验结果显示，年龄、合并症、治疗类型、对治疗的满意度、不良反应经历与健康素养与药物依从性之间存在显著关系（所有 P 值均<0.05）。逐步多元线性回归最终构建的模型具有高度统计学意义。最终模型中最高的β系数属于总健康素养评分。
根据研究结果，伊朗银屑病患者的药物依从性较低。健康素养与药物依从性相关性最强，是确定药物依从性的最佳变量。卫生政策制定者应考虑改善互联网和信通技术的获取，以提高患者的健康素养，同时发展患者教育方法和技术。
