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对马尔堡病毒的睿智洞察:聚焦近期发现的批判性综述

Sagacious Perceptive on Marburg Virus Foregrounding the Recent Findings: A Critical Review.

作者信息

Baby Bilha, Rajendran Rajalakshmi, Nair Manju M, Raghavan Roshni P

机构信息

Amrita School of Pharmacy, Amrita VishwaVidyapeetham, AIMS Health Sciences Campus, AIMS P. O. Ponekkara, Kochi, Kerala-682041, India.

出版信息

Infect Disord Drug Targets. 2022;22(8):13-18. doi: 10.2174/1871526522666220510103618.

DOI:10.2174/1871526522666220510103618
PMID:35538802
Abstract

Infectious diseases are defined as a group of diseases caused by any infecting microorganism which are highly potent to severely affect human life. The end can vary from critical infection to mortality. Most infectious diseases are reported with a rapid rate of transmission. Marburg virus disease is a kind of infectious viral disease usually manifested as hemorrhagic fever. The latest reported case of Marburg virus disease confirmed by WHO was on 6th August 2021 in the south-western province of Guinea. Marburg virus disease exhibit similar manifestations to that of infection with the Ebola virus. Though not widely spread to emerge as a pandemic, Marburg virus disease remains a serious threat to human life. This review emphasizes the novel current facts determined through various studies related to Marburg virus infection. From these promising theories, the review tries to put forward the importance of various study conclusions, which are likely to have a major impact on the health sector in the near future.

摘要

传染病被定义为一组由任何感染性微生物引起的疾病,这些微生物极具威力,会严重影响人类生命。其结局可能从严重感染到死亡不等。大多数传染病的传播速度都很快。马尔堡病毒病是一种通常表现为出血热的传染性病毒病。世界卫生组织确认的最新一例马尔堡病毒病报告于2021年8月6日发生在几内亚西南部省份。马尔堡病毒病与感染埃博拉病毒表现出相似的症状。尽管马尔堡病毒病没有广泛传播成为大流行,但它仍然对人类生命构成严重威胁。本综述强调了通过与马尔堡病毒感染相关的各种研究确定的最新事实。基于这些有前景的理论,本综述试图提出各种研究结论的重要性,这些结论可能在不久的将来对卫生部门产生重大影响。

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Antiviral Res. 2021 Nov;195:105180. doi: 10.1016/j.antiviral.2021.105180. Epub 2021 Sep 20.
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Seroprevalence and associated risk factors of selected zoonotic viral hemorrhagic fevers in Tanzania.坦桑尼亚部分人畜共患病毒性出血热的血清流行率及相关危险因素。
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Natural history of disease in cynomolgus monkeys exposed to Ebola virus Kikwit strain demonstrates the reliability of this non-human primate model for Ebola virus disease.
感染埃博拉病毒基奎特株的食蟹猴的疾病自然史表明,该非人灵长类动物模型对于埃博拉病毒病具有可靠性。
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