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传染病症状监测:印刷可穿戴传感器的前景

Monitoring Symptoms of Infectious Diseases: Perspectives for Printed Wearable Sensors.

作者信息

Al-Halhouli Ala'aldeen, Albagdady Ahmed, Alawadi Ja'far, Abeeleh Mahmoud Abu

机构信息

NanoLab/Mechatronics Engineering Department, School of Applied Technical Sciences, German Jordanian University (GJU), Amman 11180, Jordan.

Institute of Microtechnology, Technische Universität Braunschweig, 38124 Braunschweig, Germany.

出版信息

Micromachines (Basel). 2021 May 27;12(6):620. doi: 10.3390/mi12060620.

Abstract

Infectious diseases possess a serious threat to the world's population, economies, and healthcare systems. In this review, we cover the infectious diseases that are most likely to cause a pandemic according to the WHO (World Health Organization). The list includes COVID-19, Crimean-Congo Hemorrhagic Fever (CCHF), Ebola Virus Disease (EBOV), Marburg Virus Disease (MARV), Lassa Hemorrhagic Fever (LHF), Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS), Nipah Virus diseases (NiV), and Rift Valley fever (RVF). This review also investigates research trends in infectious diseases by analyzing published research history on each disease from 2000-2020 in PubMed. A comprehensive review of sensor printing methods including flexographic printing, gravure printing, inkjet printing, and screen printing is conducted to provide guidelines for the best method depending on the printing scale, resolution, design modification ability, and other requirements. Printed sensors for respiratory rate, heart rate, oxygen saturation, body temperature, and blood pressure are reviewed for the possibility of being used for disease symptom monitoring. Printed wearable sensors are of great potential for continuous monitoring of vital signs in patients and the quarantined as tools for epidemiological screening.

摘要

传染病对世界人口、经济和医疗保健系统构成严重威胁。在本综述中,我们涵盖了世界卫生组织(WHO)认定的最有可能引发大流行的传染病。清单包括新冠病毒病(COVID-19)、克里米亚-刚果出血热(CCHF)、埃博拉病毒病(EBOV)、马尔堡病毒病(MARV)、拉沙热(LHF)、中东呼吸综合征(MERS)、严重急性呼吸综合征(SARS)、尼帕病毒病(NiV)和裂谷热(RVF)。本综述还通过分析2000年至2020年在PubMed上发表的关于每种疾病的研究历史,调查传染病的研究趋势。对包括苯胺印刷、凹版印刷、喷墨印刷和丝网印刷在内的传感器印刷方法进行了全面综述,以便根据印刷规模、分辨率、设计修改能力和其他要求,为最佳方法提供指导。对用于呼吸频率、心率、血氧饱和度、体温和血压的印刷传感器进行了综述,探讨其用于疾病症状监测的可能性。印刷可穿戴传感器在持续监测患者和隔离人员生命体征方面具有巨大潜力,可作为流行病学筛查工具。

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