四（4-磺酸苯基）卟啉在由中性二酰基磷脂酰胆碱组成的脂质体表面的吸附及环糊精介导的释放
Adsorption of tetrakis(4-sulfophenyl)porphyrin onto liposomal surfaces composed of neutral diacylphosphatidylcholine and release by cyclodextrin.
作者信息
Tsuchiya Yuki, Nakaya Toshimi, Kakigi Tomoyuki, Sugikawa Kouta, Ikeda Atsushi
机构信息
Department of Applied Chemistry, Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama Higashi-Hiroshima 739-8527 Japan.
出版信息
RSC Adv. 2018 Mar 27;8(22):11930-11934. doi: 10.1039/c8ra01411f. eCollection 2018 Mar 26.
Anionic tetrakis(4-sulfophenyl)porphyrin (TPPS) interacts with liposomal surfaces composed of neutral diacylphosphatidylcholine at high lipid concentrations. TPPS interacted with liposomal surfaces through four contact points. The association constant was obtained to be 9.0 × 10 M. TPPS was peeled off the liposomal surfaces by the addition of cyclodextrin.
阴离子四（4-磺酸苯基）卟啉（TPPS）在高脂质浓度下与由中性二酰基磷脂酰胆碱组成的脂质体表面相互作用。TPPS通过四个接触点与脂质体表面相互作用。获得的缔合常数为9.0×10 M。通过添加环糊精，TPPS从脂质体表面剥离。
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