Ramalingam G, Saravanan K Venkata, Vizhi T Kayal, Rajkumar M, Baskar Kathirvelu
Department of Nanoscience and Technology, Alagappa University Karaikudi Tamil Nadu India 630 003
Department of Physics, Central University of Tamil Nadu Thiruvarur Tamil Nadu India 610 101
RSC Adv. 2018 Feb 23;8(16):8516-8527. doi: 10.1039/c7ra13400b.
Many synthesized semiconductor QDs materials are formed using trioctylphosphine oxide (TOPO) but it requires high temperature, is very expensive and is also hydrophobic. Our study deals with selective syntheses of CdSe and core-shell CdSe/ZnS quantum dots (QDs) in aqueous solution by a simple heating and refluxing method. It is more hydrophilic, needs less temperature, is economically viable and is eco-friendly. Bio-ligands, such as thioacetamide, itaconic acid and glutathione, were used as stabilizers for the biosynthesis of QDs. A simplified aqueous route was used to improve the quality of the colloidal nanocrystals. As a result, highly monodisperse, photoluminescent and biocompatible nanoparticles were obtained. The synthesized QDs were characterized by XRD, FTIR, confocal microscopy, ultraviolet (UV) absorption and photoluminescence (PL). The size of synthesized QDs was observed as 5.74 nm and the core-shell shape was confirmed by using XRD and confocal microscopy respectively. The QD nanoparticles showed antibacterial activity against pathogenic bacteria. The QDs could be applied for biological labelling, fluorescence bio-sensing and bio-imaging
许多合成的半导体量子点材料是使用三辛基氧化膦（TOPO）形成的，但它需要高温，非常昂贵且具有疏水性。我们的研究涉及通过简单的加热回流法在水溶液中选择性合成CdSe和核壳型CdSe/ZnS量子点（QDs）。它更具亲水性，所需温度更低，经济可行且环保。生物配体，如硫代乙酰胺、衣康酸和谷胱甘肽，被用作量子点生物合成的稳定剂。采用简化的水相路线来提高胶体纳米晶体的质量。结果，获得了高度单分散、光致发光且具有生物相容性的纳米颗粒。通过XRD、FTIR、共聚焦显微镜、紫外（UV）吸收和光致发光（PL）对合成的量子点进行了表征。观察到合成量子点的尺寸为5.74 nm，分别通过XRD和共聚焦显微镜确认了核壳形状。量子点纳米颗粒对病原菌表现出抗菌活性。量子点可用于生物标记、荧光生物传感和生物成像。
