Wei Xiuzhen, Bao Xiaoyan, Wu Jiawei, Li Cuixia, Shi Yingying, Chen Jinyuan, Lv Bosheng, Zhu Baoku
College of Environment, Zhejiang University of Technology Hangzhou 310014 China
Key Laboratory of Microbial Technology for Industrial Pollution Control of Zhejiang Province China.
RSC Adv. 2018 Mar 14;8(19):10396-10408. doi: 10.1039/c8ra00519b. eCollection 2018 Mar 13.
The rejection behaviors of two different charged composite hollow fiber nanofiltration (NF) membranes for six pharmaceutical molecules, primidone, carbamazepine, sulfamethoxazole, atenolol, sulfadimidine and norfloxacin, were characterized in this study. The saturation adsorption behaviors of the different pharmaceutical molecules on each membrane surface were studied and found to be related to the molecular weight, charge and hydrophilicity of the pharmaceutical molecules. After the pharmaceutical molecules reached adsorption equilibrium, the rejection rates of different NF membranes were characterized. The rejection rates of primidone, carbamazepine, sulfamethoxazole, atenolol, sulfadimidine and norfloxacin by the PEI-NF membrane were 85.6%, 91.8%, 79.9%, 98.1%, 93.3%, and 97.1%, respectively. Meanwhile, the rejection rates of the pharmaceutical molecules by the PIP-NF membrane were 82.2%, 85.4%, 91.5%, 79.1%, 87% and 93.3%, respectively. The influence of feed concentration, operation pressure, temperature, pH and ionic strength on the rejection behaviors of the different charged NF membranes were also studied.
本研究表征了两种不同带电的复合中空纤维纳滤（NF）膜对六种药物分子（扑米酮、卡马西平、磺胺甲恶唑、阿替洛尔、磺胺二甲嘧啶和诺氟沙星）的截留行为。研究了不同药物分子在各膜表面的饱和吸附行为，发现其与药物分子的分子量、电荷和亲水性有关。药物分子达到吸附平衡后，表征了不同纳滤膜的截留率。PEI-NF膜对扑米酮、卡马西平、磺胺甲恶唑、阿替洛尔、磺胺二甲嘧啶和诺氟沙星的截留率分别为85.6%、91.8%、79.9%、98.1%、93.3%和97.1%。同时，PIP-NF膜对药物分子的截留率分别为82.2%、85.4%、91.5%、79.1%、87%和93.3%。还研究了进料浓度、操作压力、温度、pH值和离子强度对不同带电纳滤膜截留行为的影响。
