Cohen-Cole S A, Stoudemire A
Psychiatr Clin North Am. 1987 Mar;10(1):1-17.
Major depression is a painful and debilitating condition that often occurs in association with severe physical illness. Accurate diagnosis is problematic because sadness is a frequent "normal" reaction to physical illness and because many other symptoms of depression, such as anorexia and fatigue, can also be caused by the physical illnesses themselves. We review the clinical research that helps to clarify these diagnostic issues and present guidelines for the diagnosis and biologic treatment of patients with concomitant major depression and physical illness.
重度抑郁症是一种痛苦且使人衰弱的病症，常与严重躯体疾病并发。准确诊断存在问题，因为悲伤是对躯体疾病常见的“正常”反应，且抑郁症的许多其他症状，如厌食和疲劳，也可能由躯体疾病本身引起。我们回顾了有助于阐明这些诊断问题的临床研究，并提出了同时患有重度抑郁症和躯体疾病患者的诊断及生物治疗指南。
