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[慢性γ辐射对生活在放射性增强栖息地的根田鼠及其后代组织中脱氢酶活性的影响]

[Effect of chronic gamma irradiation on dehydrogenase activity in the tissues of root voles and their progeny dwelling in a habitat with increased radioactivity].

作者信息

Pikulev A T, Kudiasheva A G, Taskaev A I

出版信息

Radiobiologiia. 1987 Mar-Apr;27(2):218-23.

PMID:3554319
Abstract

Chronic gamma-irradiation during 3.5 and 6 months (at a dose = rate of 46.2 pC/kg X c) of Microtus oeconomus living in conditions of normal and increased (by 50-100 times) gamma-radiation background, and of their progeny (the 1st, 2nd, 3d, and 4th generations) causes in homogenates of cardiac muscle, liver, and brain different changes in activity of succinate dehydrogenase (1.3.99.1, EC), pyruvate dehydrogenase (1.2.4.1, EC), and lactate dehydrogenase (1.1.1.27, EC) associated with the discordance of the processes of tissue respiration and glycolysis. The changes in dehydrogenases activity in Microtus oeconomus subjected to chronic irradiation were nearly the same as those found in their parents.

摘要

对生活在正常和增加(50 - 100倍)γ辐射背景条件下的田鼠进行3.5个月和6个月的慢性γ辐射(剂量率为46.2 pC/kg X c),及其后代(第1、2、3和4代),会导致心肌、肝脏和脑组织匀浆中琥珀酸脱氢酶(1.3.99.1,EC)、丙酮酸脱氢酶(1.2.4.1,EC)和乳酸脱氢酶(1.1.1.27,EC)的活性发生不同变化,这些变化与组织呼吸和糖酵解过程的不协调有关。受到慢性辐射的田鼠体内脱氢酶活性的变化与其亲代中发现的变化几乎相同。

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