具有混合 ROS 的水溶性亮近红外 AIEgens，用于免洗线粒体“开-关”成像和光动力治疗。
Water-soluble bright NIR AIEgens with hybrid ROS for wash-free mitochondrial "off-on" imaging and photodynamic therapy.
机构信息
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, P. R. China.
NingboTech University, Ningbo, 315100, Zhejiang, P. R. China.
出版信息
Chem Commun (Camb). 2022 May 30;58(44):6393-6396. doi: 10.1039/d2cc01559e.
Several aggregation-induced emission luminogens (AIEgens) with excellent water-solubility and near-infrared emission were designed and synthesized for wash-free "off-on" mitochondrial imaging and photodynamic therapy of HeLa cells. The AIEgen TEPP exhibits both bright near-infrared emission ( = 17.8%) and high hybrid ROS productivity (including OH˙ and O).
几种具有良好水溶性和近红外发射的聚集诱导发光材料（AIEgens）被设计和合成，用于 HeLa 细胞无冲洗的线粒体成像和光动力治疗。AIEgen TEPP 表现出明亮的近红外发射（ = 17.8%）和高混合 ROS 生成能力（包括 OH˙和 O）。
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