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休克指数和评分系统对预测老年上消化道出血患者死亡率的影响:一项前瞻性队列研究。

The effect of the shock index and scoring systems for predicting mortality among geriatric patients with upper gastrointestinal bleeding: a prospective cohort study.

机构信息

MD. Emergency Medicine Specialist, Department of Emergency Medicine, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.

MD. Associate Professor of Emergency Medicine, Department of Emergency Medicine, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.

出版信息

Sao Paulo Med J. 2022 Jul-Aug;140(4):531-539. doi: 10.1590/1516-3180.2021.0735.13102021.

Abstract

BACKGROUND

Gastrointestinal (GI) bleeding is an important cause of mortality and morbidity among geriatric patients.

OBJECTIVE

To investigate whether the shock index and other scoring systems are effective predictors of mortality and prognosis among geriatric patients presenting to the emergency department with complaints of upper GI bleeding.

DESIGN AND SETTING

Prospective cohort study in an emergency department in Bursa, Turkey.

METHODS

Patients over 65 years admitted to a single-center, tertiary emergency service between May 8, 2019, and April 30, 2020, and diagnosed with upper GI bleeding were analyzed. 30, 180 and 360-day mortality prediction performances of the shock index and the Rockall, Glasgow-Blatchford and AIMS-65 scores were evaluated.

RESULTS

A total of 111 patients who met the criteria were included in the study. The shock index (P < 0.001) and AIMS-65 score (P < 0.05) of the patients who died within the 30-day period were found to be significantly different, while the shock index (P < 0.001), Rockall score (P < 0.001) and AIMS-65 score (P < 0.05) of patients who died within the 180-day and 360-day periods were statistically different. In the receiver operating characteristic (ROC) analysis for predicting 360-day mortality, the area under the curve (AUC) value was found to be 0.988 (95% confidence interval, CI, 0.971-1.000; P < 0.001).

CONCLUSION

The shock index measured among geriatric patients with upper GI bleeding at admission seems to be a more effective predictor of prognosis than other scoring systems.

摘要

背景

胃肠道(GI)出血是老年患者死亡和发病的重要原因。

目的

探讨休克指数和其他评分系统是否能有效预测因上消化道出血到急诊科就诊的老年患者的死亡率和预后。

设计和设置

在土耳其布尔萨的一家急诊科进行的前瞻性队列研究。

方法

分析 2019 年 5 月 8 日至 2020 年 4 月 30 日期间在单一中心三级急诊服务机构就诊并诊断为上消化道出血的年龄超过 65 岁的患者。评估休克指数和 Rockall、Glasgow-Blatchford 和 AIMS-65 评分对 30、180 和 360 天死亡率的预测性能。

结果

共有 111 名符合条件的患者纳入研究。在 30 天内死亡的患者的休克指数(P < 0.001)和 AIMS-65 评分(P < 0.05)差异有统计学意义,而在 180 天和 360 天内死亡的患者的休克指数(P < 0.001)、Rockall 评分(P < 0.001)和 AIMS-65 评分(P < 0.05)差异有统计学意义。在预测 360 天死亡率的受试者工作特征(ROC)分析中,曲线下面积(AUC)值为 0.988(95%置信区间,CI,0.971-1.000;P < 0.001)。

结论

在因上消化道出血到急诊科就诊的老年患者中测量的休克指数似乎比其他评分系统更能有效预测预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a889/9491474/bd851fa073fb/1806-9460-spmj-1516-3180-2021-0735-13102021-gf1.jpg

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