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COVID-19 患者在皮质类固醇治疗中潜伏性结核的再激活。

Reactivation of latent tuberculosis in a COVID-19 patient on corticosteroid treatment.

机构信息

Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA

Family Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.

出版信息

BMJ Case Rep. 2022 May 11;15(5):e247562. doi: 10.1136/bcr-2021-247562.

Abstract

Though the COVID-19 pandemic has made international headlines since 2020, behind the scenes, tuberculosis (TB) has remained a leading cause of global mortality. According to the WHO, TB is 1 of the top 10 causes of death globally, with about one-quarter of the world's population infected. This case report highlights a female patient who presented to the emergency department with signs and symptoms of COVID-19 and was admitted to hospital. When the patient demonstrated minimal clinical improvement after initiating treatment for COVID-19, further investigations uncovered concomitant reactivated TB. This case is helpful in underscoring the potential implications of the COVID-19 pandemic and current treatment guidelines on the global burden of TB, which could subsequently impact how practitioners approach screening and management of latent TB infection.

摘要

尽管 2020 年以来,COVID-19 疫情一直占据国际头条,但在幕后,结核病(TB)仍然是全球死亡的主要原因之一。根据世界卫生组织的数据,结核病是全球十大死因之一,全球约有四分之一的人口感染。本病例报告重点介绍了一位女性患者,她因 COVID-19 的症状和体征到急诊就诊,并住院治疗。当患者在开始 COVID-19 治疗后表现出最小的临床改善时,进一步的调查发现同时发生了复发性结核病。本病例有助于强调 COVID-19 大流行和当前治疗指南对全球结核病负担的潜在影响,这可能会影响临床医生如何进行潜伏性结核病感染的筛查和管理。

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本文引用的文献

7
Tuberculosis: latency and reactivation.结核病:潜伏与再激活
Infect Immun. 2001 Jul;69(7):4195-201. doi: 10.1128/IAI.69.7.4195-4201.2001.

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