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自发性冠状动脉夹层中的抗凝与抗血小板治疗难题。

The Conundrum of Anticoagulation and Antiplatelet Therapy in Spontaneous Coronary Artery Dissection.

机构信息

Department of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA.

Division of Cardiology, SUNY Upstate Medical University, Syracuse, NY, USA.

出版信息

J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221097541. doi: 10.1177/23247096221097541.

Abstract

Spontaneous coronary artery dissection (SCAD) is a relatively rare and frequently misdiagnosed disease. The current knowledge of its pathophysiology and management is limited and based mostly on hypotheses. We present a patient with recurrent SCAD whose condition worsened soon after discontinuation of anticoagulation, prompting us to question the current management and review the evidence about pathophysiology, anticoagulation, and antiplatelet therapy.

摘要

自发性冠状动脉夹层 (SCAD) 是一种相对罕见且经常被误诊的疾病。目前对其病理生理学和治疗的认识有限,主要基于假设。我们介绍了一位反复发生 SCAD 的患者,在停止抗凝治疗后不久病情恶化,这促使我们质疑当前的治疗方法,并回顾关于病理生理学、抗凝和抗血小板治疗的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0911/9112293/9c6125455944/10.1177_23247096221097541-fig1.jpg

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