The Hormel Institute, 5635University of Minnesota, Austin, MN, USA.
Masonic Cancer Center, 5635University of Minnesota, Minneapolis, MN, USA.
Technol Cancer Res Treat. 2022 Jan-Dec;21:15330338221097203. doi: 10.1177/15330338221097203.
Hepatobiliary cancers comprise a wide range of malignancies such as hepatocellular carcinoma and cholangiocarcinoma, and they are some of the most challenging to treat human neoplasms. Due to the rarity of the illnesses, the development of treatment measures for malignancies of the gastrointestinal system is far behind. The number of patients eligible for curative treatment is limited due to cancer's aggressive nature and the difficulties of early identification. Furthermore, surgery is frequently intrusive and linked with a significant level of risk. The therapy result of hepatobiliary cancers is unsatisfactory due to these complicated variables, leaving significant space for improvement.
肝胆癌包括多种恶性肿瘤,如肝细胞癌和胆管癌,它们是最难治疗的人类肿瘤之一。由于这些疾病较为罕见,胃肠道系统恶性肿瘤的治疗措施的发展远远落后。由于癌症的侵袭性和早期识别的困难,适合治愈性治疗的患者数量有限。此外,手术常常具有侵入性,并伴随着相当大的风险。由于这些复杂的变量,肝胆癌的治疗效果并不理想,还有很大的改进空间。