Mittler J, Heinrich S, Lang H
Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsmedizin Mainz, Langenbeckstraße 1, 55131, Mainz, Deutschland.
Chirurg. 2018 Nov;89(11):865-871. doi: 10.1007/s00104-018-0733-z.
Primary hepatobiliary malignancies are hepatocellular carcinoma, cholangiocarcinoma and the rare hepatocellular cholangiocarcinoma (mixed tumor). The indications for liver transplantation and the oncological prognosis differ considerably between these tumor entities. Treatment and decision making for these tumors are often complicated by an underlying chronic liver disease. The aim of this review is to delineate the indications for transplantation and bridging therapies for each cancer entity as well as to highlight some aspects pertinent to transplantation, such as the principles of organ allocation.
原发性肝胆恶性肿瘤包括肝细胞癌、胆管癌以及罕见的肝细胞胆管癌（混合性肿瘤）。这些肿瘤实体在肝移植指征和肿瘤学预后方面存在显著差异。这些肿瘤的治疗和决策常常因潜在的慢性肝病而变得复杂。本综述的目的是阐明每种癌症实体的移植指征和桥接治疗方法，并强调与移植相关的一些方面，如器官分配原则。
