is a rich source of high-value plant secondary metabolites that have been used in the treatment of various ailments since ancient times. Herein, we report the conversion of bulk Ag ions into highly potent organometallic Ag nanostructures (OM-Ag-NS) using extract as a phytochelating agent for the first time. Analysis by X-ray diffraction (XRD) of OM-Ag-NS revealed that they are of a hybrid nature and include pure Ag crystal planes and Ag-organic-complex crystal planes. An investigation by scanning electron microscopy (SEM) of the NS revealed the rough nanocube-like morphology of OM-Ag-NS with an average particle size of 32 nm. Ultra-performance liquid chromatography-diode array detector (UPLC-DAD) and Fourier transform infrared (FTIR) spectroscopy of extract and the residue validated the utilization of phytochelating compounds in the synthesis process of OM-Ag-NS. Thermogravimetric analysis (TGA) supplemented the findings of UPLC-DAD and showed the thermal loss of the organic capping agent around OM-Ag-NS between 300 and 320 °C. NanoDrop-ultraviolet and visible (UV) spectroscopic analysis showed that the tailored bandgap energy of OM-Ag-NS was 2.82 eV. Moreover, compared with chemically stabilized Ag nanostructures (CS-Ag-NS), OM-Ag-NS exhibited promising performance against highly virulent multidrug-resistant (NDM-1) and (KPC). Our current findings suggest that is a top candidate for tailoring the potential of NS towards various biological activities.