从短芽孢杆菌（NCIM 2533）中合成银纳米粒子及其对致病菌的抗菌活性。
Synthesis of silver nanoparticles from Bacillus brevis (NCIM 2533) and their antibacterial activity against pathogenic bacteria.
机构信息
Department of Medical Microbiology and Immunology, Institute of Biomedical Sciences, College of Health Science, Mekelle University, Ethiopia; Department of Biotechnology, SRM University, SRM Nagar, Kattankulathur, Chennai, Tamil Nadu 603 203, India.
Department of Biotechnology, SRM University, SRM Nagar, Kattankulathur, Chennai, Tamil Nadu 603 203, India.
出版信息
Microb Pathog. 2018 Mar;116:221-226. doi: 10.1016/j.micpath.2018.01.038. Epub 2018 Jan 31.
The present study is focused on the biological synthesis of silver nanoparticles (AgNPs) from the Bacillus brevis (NCIM 2533) was investigated. The synthesized AgNPs were characterized by various spectroscopic and microscopic techniques and confirmed the AgNPs having the surface Plasmon resonance peak at 420 nm and in the size range of 41-68 nm with spherical in shape by AFM and SEM analysis. It was confirmed and ascertained the presence of bioactive compounds in the AgNPs using TLC and FTIR. The In-vitro antibacterial activity of AgNPs showaed potential antibacterial property against multi-drug resistant pathogens such as Salmonella typhi and Staphylococcus aureus. The biosynthesized AgNPs could be utilized as antimicrobial agents for effective disease management.
本研究聚焦于从短芽孢杆菌（NCIM 2533）中生物合成银纳米粒子（AgNPs）。合成的 AgNPs 通过各种光谱和显微镜技术进行了表征，并通过 AFM 和 SEM 分析证实 AgNPs 在 420nm 处具有表面等离子体共振峰，且尺寸在 41-68nm 范围内呈球形。通过 TLC 和 FTIR 证实并确定了 AgNPs 中存在生物活性化合物。AgNPs 的体外抗菌活性显示出对多种耐药病原体（如伤寒沙门氏菌和金黄色葡萄球菌）的潜在抗菌特性。生物合成的 AgNPs 可作为有效的疾病管理的抗菌剂。
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