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双侧睾丸受累酷似睾丸癌的结节病:一例罕见病例报告

Sarcoidosis With Bilateral Testicular Involvement Resembling Testicular Cancer: A Rare Case Report.

作者信息

Hacıosmanoğlu Taner, Türk Semih, Baloğlu İbrahim H, Yavuzsan Eminegül, Yavuzsan Abdullah H

机构信息

Urology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, TUR.

Pulmonology and Critical Care, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, TUR.

出版信息

Cureus. 2022 Apr 9;14(4):e23982. doi: 10.7759/cureus.23982. eCollection 2022 Apr.

DOI:10.7759/cureus.23982
PMID:35547417
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9090139/
Abstract

Sarcoidosis is a granulomatous inflammatory disease that could potentially involve multiple organ systems. It causes noncaseating granulomas in tissues, and at least two organs must be involved to make a diagnosis. In sarcoidosis patients, if there is a mass in the testicles, a testicular biopsy should be performed to exclude malignancies because of infrequent testicular involvement. We present a 23-year-old male diagnosed with sarcoidosis who had a bilateral testicular mass. A testicular biopsy was performed because of bilateral involvement. The biopsy revealed a diagnosis of sarcoidosis. After high-dose steroid treatment, the lesions regressed. This paper presents a sarcoidosis case with testicular involvement that imitates testicular tumors. Testicular tumors and testicular involvement of sarcoidosis are two different pathologies that may mimic each other, confuse clinicians, and/or lead to misdiagnosis and mistreatment.

摘要

结节病是一种可能累及多个器官系统的肉芽肿性炎症性疾病。它会在组织中形成非干酪样肉芽肿,且诊断时至少必须累及两个器官。在结节病患者中,如果睾丸出现肿块,由于睾丸受累情况不常见,应进行睾丸活检以排除恶性肿瘤。我们报告一例23岁诊断为结节病的男性患者,其双侧睾丸有肿块。因双侧受累而进行了睾丸活检。活检结果显示为结节病。高剂量类固醇治疗后,病变消退。本文介绍了一例模仿睾丸肿瘤的结节病累及睾丸的病例。睾丸肿瘤和结节病累及睾丸是两种不同的病理情况,它们可能相互模仿,使临床医生感到困惑,和/或导致误诊和误治。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/5ad432230d02/cureus-0014-00000023982-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/0f73e658cfea/cureus-0014-00000023982-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/edadd98848c5/cureus-0014-00000023982-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/28f8cb2b160a/cureus-0014-00000023982-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/5ad432230d02/cureus-0014-00000023982-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/0f73e658cfea/cureus-0014-00000023982-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/edadd98848c5/cureus-0014-00000023982-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/28f8cb2b160a/cureus-0014-00000023982-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/154e/9090139/5ad432230d02/cureus-0014-00000023982-i04.jpg

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引用本文的文献

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本文引用的文献

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Diagnosis and Treatment of Pulmonary Sarcoidosis: A Review.肺结节病的诊断与治疗:综述。
JAMA. 2022 Mar 1;327(9):856-867. doi: 10.1001/jama.2022.1570.
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A Rare Case of Sarcoidosis Involving Male Breast Tissue.一例累及男性乳腺组织的结节病罕见病例。
Cureus. 2022 Jan 18;14(1):e21387. doi: 10.7759/cureus.21387. eCollection 2022 Jan.
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Treatment of a Gastrointestinal Sarcoidosis Flare: A Multidisciplinary Approach for a Multisystem Disease.胃肠道肉样瘤病发作的治疗:一种针对多系统疾病的多学科方法。
Am J Case Rep. 2021 Sep 23;22:e932494. doi: 10.12659/AJCR.932494.
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Sarcoidosis: Causes, Diagnosis, Clinical Features, and Treatments.结节病:病因、诊断、临床特征及治疗
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Sarcoidosis is a rare cause of infertility: A case report.结节病是导致不孕的罕见原因:一例病例报告。
Urol Case Rep. 2019 Nov 1;28:101065. doi: 10.1016/j.eucr.2019.101065. eCollection 2020 Jan.
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Testicular sarcoidosis.睾丸结节病
Urol Case Rep. 2018 Feb 3;17:109-110. doi: 10.1016/j.eucr.2018.01.021. eCollection 2018 Mar.
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Pulmonary sarcoidosis with and without extrapulmonary involvement: a cross-sectional and observational study in China.有和无肺外受累的肺结节病:一项在中国的横断面观察性研究。
BMJ Open. 2018 Feb 16;8(2):e018865. doi: 10.1136/bmjopen-2017-018865.
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Radiol Case Rep. 2015 Dec 7;7(3):685. doi: 10.2484/rcr.v7i3.685. eCollection 2012.
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A diagnostic dilemma: metastatic testicular cancer and systemic sarcoidosis - a review of the literature.诊断难题:转移性睾丸癌与系统性结节病——文献综述
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