正电子发射断层扫描/计算机断层扫描中氟代脱氧葡萄糖放射性药物所致胚胎/胎儿剂量
Embryo/Fetus Doses from F-Fludeoxyglucose Radiopharmaceutical in Positron Emission Tomography/ Computed Tomography.
作者信息
Işıkçı Nazenin İpek, Demir Mustafa
机构信息
Department of Electrical and Electronics Engineering, Faculty of Engineering and Architecture, Nisantasi University, Istanbul, Turkey.
Department of Nuclear Medicine, Faculty of Cerrahpasa Medical, Istanbul University-Cerrahpasa, Istanbul, Turkey.
出版信息
J Med Phys. 2022 Jan-Mar;47(1):109-113. doi: 10.4103/jmp.jmp_115_21. Epub 2022 Mar 31.
AIM
The embryo/fetus may be accidentally exposed to ionizing radiation. The aim of this study is to calculate embryo/fetus doses in pregnant women who underwent F-18 fludeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan.
MATERIALS AND METHODS
Between June 2015 and June 2021, 15 pregnant women underwent F-18 FDG PET/CT applied to the Genetic Research Center (GETAM). The OLINDA/EXM package program was used for internal radiation dosimetry according to the Medical Internal Radiation Dose scheme. FetDose V4 computer software was used to compute the embryo/fetus absorbed dose from CT scan.
RESULTS
The amount of the injected F-18 FDG activity to patients varied between 333 and 555 MBq. The mean embryo/fetal dose from F-18 FDG was 7.2 ± 2.8 mGy. In addition, the CT component dose to the embryo/fetus dose ranged from 8.5 to 16 mGy with a mean of 12.14 ± 2.05.
CONCLUSIONS
The embryo/fetus dose from F-18 FDG PET/CT was <15 mGy, however, questioning the women's childbearing prior to scintigraphy is the first-line strategy to avoid accidental radiation exposure and stochastic risks.
目的
胚胎/胎儿可能会意外暴露于电离辐射。本研究的目的是计算接受F-18氟脱氧葡萄糖（FDG）正电子发射断层扫描/计算机断层扫描（PET/CT）的孕妇的胚胎/胎儿剂量。
材料与方法
2015年6月至2021年6月期间，15名孕妇在遗传研究中心（GETAM）接受了F-18 FDG PET/CT检查。根据医学内照射剂量方案，使用OLINDA/EXM软件包程序进行内照射剂量测定。使用FetDose V4计算机软件计算CT扫描产生的胚胎/胎儿吸收剂量。
结果
患者注射的F-18 FDG活度在333至555 MBq之间。F-18 FDG产生的平均胚胎/胎儿剂量为7.2±2.8 mGy。此外，CT部分对胚胎/胎儿的剂量范围为8.5至16 mGy，平均为12.14±2.05。
结论
F-18 FDG PET/CT产生的胚胎/胎儿剂量<15 mGy，然而，在闪烁扫描前询问女性的生育情况是避免意外辐射暴露和随机风险的一线策略。
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