Wang Keli, Wang Yanping, Wang Chongwen, Jia Xiaofei, Li Jia, Xiao Rui, Wang Shengqi
Anhui Medical University Hefei 230032 PR China
Beijing Institute of Radiation Medicine Beijing 100850 PR China
RSC Adv. 2018 Sep 3;8(54):30825-30831. doi: 10.1039/c8ra05213a. eCollection 2018 Aug 30.
This study proposes a facile and general method for fabricating a wide range of high-performance SiO@Au core-shell nanoparticles (NPs). The thicknesses of Au shells can be easily controlled, and the process of Au shell formation was completed within 5 min through sonication. The fabricated SiO@Au NPs with highly uniform size and SERS activity could be ideal SERS tags for SERS-based immunoassay.
本研究提出了一种简便通用的方法来制备多种高性能的SiO@Au核壳纳米粒子(NPs)。金壳的厚度可以轻松控制,并且通过超声处理在5分钟内即可完成金壳的形成过程。所制备的尺寸高度均匀且具有表面增强拉曼散射(SERS)活性的SiO@Au NPs可成为基于SERS的免疫分析的理想SERS标签。