Ye Weitao, Yang Wanqun, Guo Chengwei, Dong Chenyu, Shi Feng, Liang Changhong
Department of Radiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangdong, People's Republic of China.
Department of Radiology, 82 Group Hospital of PLA, Hebei, Province, People's Republic of China.
Diagn Interv Radiol. 2022 Mar;28(2):115-123. doi: 10.5152/dir.2022.20292.
PURPOSE We aimed to explore the effect of microwave ablation (MWA) protocols upon morphology and instant changes in intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters on MWA zones in porcine livers. METHODS According to the empirical protocol for MWA in tumors less than 3 cm in our hospital, the power and application duration were assigned as five groups: A, 60 W × 5 min (n = 6); B, 80 W × 3 min (n = 7); C, 80 W × 5 min (n = 10); D, 100 W × 3 min (n = 10); E, 100 W × 5 min (n = 9). Spearman correlation between MWA protocols, morphological metrics, and instant post-ablation IVIM parameters was performed. RESULTS There was fair positive correlation between energy delivery and short axis (RSpearman = 0.426, P= .005) of the white zone. There was moderate-to-good positive correlation between wattage and short axis (RSpearman = 0.584, P < .001) of the white zone. For post-ablation IVIM parameters in the white zone, only wattage had moderate-to-good positive correlation with D value (RSpearman= 0.574, P < .001) or ADC value (RSpearman = 0.550, P < .001). No correlation between energy delivery, wattage, duration, and f value was observed (RSpearman = 0.185, P = .24; RSpearman= - 0.001, P = .99; RSpearman = 0.203, P = .20, respectively). CONCLUSION The increase in the short axis of the white zone is more likely to be affected by wattage than energy delivery. The instant post-ablation IVIM is feasible in monitoring the MWA zones since the f value in the white zones is not sensitive to changes in MWA protocols, which is promising in evaluating the instant effect of MWA.
我们旨在探讨微波消融（MWA）方案对猪肝脏MWA区域的形态以及体素内不相干运动（IVIM）扩散加权成像（DWI）参数即时变化的影响。方法：根据我院对直径小于3 cm肿瘤的MWA经验方案，将功率和应用持续时间分为五组：A组，60 W×5分钟（n = 6）；B组，80 W×3分钟（n = 7）；C组，80 W×5分钟（n = 10）；D组，100 W×3分钟（n = 10）；E组，100 W×5分钟（n = 9）。对MWA方案、形态学指标和消融后即时IVIM参数进行Spearman相关性分析。结果：能量传递与白色区域短轴之间存在中等程度的正相关（Spearman相关系数= 0.426，P = 0.005）。功率与白色区域短轴之间存在中度至高度正相关（Spearman相关系数= 0.584，P < 0.001）。对于白色区域消融后的IVIM参数，只有功率与D值（Spearman相关系数= 0.574，P < 0.001）或表观扩散系数（ADC）值（Spearman相关系数= 0.550，P < 0.001）存在中度至高度正相关。未观察到能量传递、功率、持续时间与f值之间的相关性（Spearman相关系数分别为0.185，P = 0.24；Spearman相关系数= - 0.001，P = 0.99；Spearman相关系数= 0.203，P = 0.20）。结论：白色区域短轴的增加更可能受功率而非能量传递的影响。消融后即时IVIM在监测MWA区域方面是可行的，因为白色区域的f值对MWA方案的变化不敏感，这在评估MWA的即时效果方面很有前景。
