足月新生儿出生后即刻无复杂新生儿过渡期的酸碱及血气分析。
Acid base and blood gas analysis in term neonates immediately after birth with uncomplicated neonatal transition.
机构信息
Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Styria, Austria.
Research Unit for Neonatal Micro- and Macrocirculation, Division of Neonatology, Medical University of Graz, Graz, Austria.
出版信息
BMC Pediatr. 2022 May 12;22(1):271. doi: 10.1186/s12887-022-03324-z.
BACKGROUND
Acid base and blood gas measurements provide essential information, especially in critically ill neonates. After birth, rapidly changing physiology and difficulty to obtain blood samples represent unique challenges.
OBJECTIVES
The aim of the present study was to establish normal values of capillary acid base and blood gas analysis immediately after birth in term neonates after uncomplicated neonatal transition.
METHOD
This is a post-hoc-analysis of ancillary outcome parameter of a prospective observational study in term neonates immediately after caesarean section. Neonates were included after immediate neonatal transition without need of medical support and a capillary blood sample was taken by a heel-stick within 15-20 minutes after birth.
RESULT
One hundred thirty-two term neonates were included with mean (SD) gestational age of 38.7 ± 0.7 weeks. The blood was drawn mean (SD) 16 ± 1.7 minutes after birth. The mean (SD) values of the analyses were: pH 7.30 ± 0.04, pCO 52.6 ± 6.4, base excess - 0.9 ± 1.7 and bicarbonate 24.8 ± 1.6.
CONCLUSION
This is the first study describing acid base and blood gas analyses in term neonates immediately after birth with uncomplicated neonatal transition.
背景
酸碱和血气测量提供了重要信息，尤其是在危重新生儿中。出生后，生理变化迅速且难以采集血样，这构成了独特的挑战。
目的
本研究旨在确立无复杂新生儿过渡期的足月新生儿出生后即刻毛细血管酸碱和血气分析的正常值。
方法
这是一项前瞻性观察研究的辅助结局参数的事后分析，研究对象为剖宫产术后即刻的足月新生儿。纳入标准为新生儿即刻完成了新生儿过渡期，无需医疗支持，且在出生后 15-20 分钟内通过足跟采血获得毛细血管血样。
结果
本研究共纳入 132 例足月新生儿，平均（SD）胎龄为 38.7±0.7 周。采血的平均（SD）时间为出生后 16±1.7 分钟。分析的平均（SD）值为：pH 7.30±0.04、pCO2 52.6±6.4、碱剩余-0.9±1.7 和碳酸氢盐 24.8±1.6。
结论
这是第一项描述无复杂新生儿过渡期的足月新生儿出生后即刻酸碱和血气分析的研究。
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