苯二氮䓬类药物的临床药理学

Annu Rev Med. 1987;38:19-28. doi: 10.1146/annurev.me.38.020187.000315.

The benzodiazepines are the most widely used anxiolytic drugs. Their pharmacokinetic properties differ widely. Side effects are usually mild but dependence can supervene after long-term administration, even if normal therapeutic doses are not exceeded. Careful monitoring of use is essential.

苯二氮䓬类药物是使用最广泛的抗焦虑药。它们的药代动力学特性差异很大。副作用通常较轻，但长期用药后可能会出现依赖性，即使未超过正常治疗剂量。必须仔细监测用药情况。