Slater R M, McLaren I D
Br J Anaesth. 1987 May;59(5):602-5. doi: 10.1093/bja/59.5.602.
In a double-blind randomized study, patients received premedication with lorazepam 0.04 mg kg-1 and salbutamol 0.1 mg kg-1 or lorazepam 0.04 mg kg-1 and placebo given orally 2.5-3 h before anaesthesia. The plasma potassium concentration was measured at the time of premedication, before the induction of anaesthesia and at selected intervals after suxamethonium 1 mg kg-1 i.v. The plasma potassium concentration was lower in those patients who received salbutamol than in those given placebo, and remained lower at all the subsequent sample times. Oral salbutamol did not appear to affect the incidence of suxamethonium related muscle pain.
在一项双盲随机研究中，患者在麻醉前2.5 - 3小时口服0.04毫克/千克的劳拉西泮和0.1毫克/千克的沙丁胺醇进行术前用药，或口服0.04毫克/千克的劳拉西泮和安慰剂。在术前用药时、麻醉诱导前以及静脉注射1毫克/千克琥珀酰胆碱后的选定时间间隔测量血浆钾浓度。接受沙丁胺醇的患者血浆钾浓度低于接受安慰剂的患者，并且在所有后续采样时间均保持较低水平。口服沙丁胺醇似乎不影响琥珀酰胆碱相关肌肉疼痛的发生率。
