Bowers R W, Tighe B J
Biomaterials. 1987 Mar;8(2):83-8. doi: 10.1016/0142-9612(87)90094-9.
The range and nature of the various clinical manifestations of hydrogel contact lens spoilations are considered. An indication of the present view of the occurrence, chemical composition and potential aetiology for discrete elevated deposits, organic and inorganic surface films, plaques and granular deposits, microbial spoilation, lens discoloration and other extrinsic factors is provided. The literature is principally concerned with the clinical manifestations of spoilation and most observations have been made on lenses that have become so severely spoiled as to be unwearable. No serious attempt has yet been made to identify those tear species responsible for the development of the various types of deposits or of the effects of variations in the bulk and lens chemistry, and also wear protocols on the formation of deposits.
本文探讨了水凝胶隐形眼镜损坏的各种临床表现的范围和性质。文中指出了目前对于离散性隆起沉积物、有机和无机表面膜、斑块和颗粒状沉积物、微生物污染、镜片变色及其他外在因素的发生、化学成分和潜在病因的观点。文献主要关注损坏的临床表现，大多数观察是针对已严重损坏到无法佩戴的镜片。目前尚未有人认真尝试确定导致各种类型沉积物形成的泪液成分，以及泪液总量和镜片化学成分变化的影响，还有佩戴方案对沉积物形成的影响。
