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基于联邦学习的医学信息学中安全电子健康记录共享方案。

Federated Learning-Based Secure Electronic Health Record Sharing Scheme in Medical Informatics.

出版信息

IEEE J Biomed Health Inform. 2023 Feb;27(2):617-624. doi: 10.1109/JBHI.2022.3174823. Epub 2023 Feb 3.

DOI:10.1109/JBHI.2022.3174823
PMID:35560105
Abstract

Medical Cyber-Physical Systems support the mobility of electronic health records data for clinical research to accelerate new scientific discoveries. Artificial Intelligence improves medical informatics, but current centralized data training and insecure data storage management techniques expose private medical data to unauthorized foreign entities. In this paper, a Federated Learning-based Electronic Health Record sharing scheme is proposed for Medical Informatics to preserve patient data privacy. A decentralized Federated Learning-based Convolutional Neural Network model trains data locally in the hospital and stores results in a private InterPlanetary File System. A secondary global model is trained at the research center using the local models. Private IPFS secures all medical data stored locally in the hospital. The novelty of this study resides in securing valuable hospital biomedical data useful for clinical research organizations. Blockchain and smart contracts enable patients to negotiate with external entities for rewards in exchange for their data. Evaluation results demonstrate that the decentralized CNN model performs better in accuracy, sensitivity, and specificity, similar to the traditional centralized model. The performance of the Private IPFS exceeds the Blockchain-based IPFS based on file upload and download time. The scheme is suitable for promoting a secure and privacy-friendly environment for sharing data with clinical research centers for biomedical research.

摘要

医疗网络物理系统支持电子健康记录数据的移动性,以加速新的科学发现。人工智能改进了医学信息学,但当前集中式的数据训练和不安全的数据存储管理技术将私人医疗数据暴露于未经授权的外国实体。在本文中,提出了一种基于联邦学习的电子健康记录共享方案,用于医学信息学以保护患者数据隐私。去中心化的基于联邦学习的卷积神经网络模型在医院内本地训练数据,并将结果存储在私有星际文件系统中。在研究中心使用本地模型训练二级全局模型。私有 IPFS 保护医院内本地存储的所有医疗数据。本研究的新颖之处在于保护对临床研究组织有用的有价值的医院生物医学数据。区块链和智能合约使患者能够与外部实体协商奖励,以换取他们的数据。评估结果表明,去中心化的 CNN 模型在准确性、敏感性和特异性方面的性能与传统的集中式模型相似。私有 IPFS 的性能在文件上传和下载时间方面优于基于区块链的 IPFS。该方案适用于为与临床研究中心共享数据促进安全和隐私友好的环境,用于生物医学研究。

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Clinical Research Informatics: Contributions from 2023.临床研究信息学:2023年的贡献。
Yearb Med Inform. 2024 Aug;33(1):143-146. doi: 10.1055/s-0044-1800733. Epub 2025 Apr 8.
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A Review of Privacy Enhancement Methods for Federated Learning in Healthcare Systems.
联邦学习中增强医疗系统隐私保护的方法综述
Int J Environ Res Public Health. 2023 Aug 7;20(15):6539. doi: 10.3390/ijerph20156539.