Sakabe K, Seiki K, Fujii-Hanamoto H, Haruki Y, Ogawa H
Endocrinol Jpn. 1986 Dec;33(6):777-85. doi: 10.1507/endocrj1954.33.777.
Progestin (P) target cells were identified in the pituitary gland of gonadectomized female rats which had been primed with estrogen (E). P staining was localized using the immunohistochemical avidin-biotin-peroxidase (ABP) complex method. Dark brown precipitates were primarily found over the cytoplasm of cells in the pars distalis, but not in the pars intermedia nor in the pars nervosa. The majority of P-sensitive cells in the pars distalis were identical with luteotrophs, a few being lactotrophs. These observations suggest a role of P in the regulation of production and secretion of gonadotrophins in the pituitary glands of female rats.
在已用雌激素（E）预处理的去性腺雌性大鼠的垂体中鉴定出孕激素（P）靶细胞。使用免疫组织化学抗生物素蛋白-生物素-过氧化物酶（ABP）复合物法对P染色进行定位。深棕色沉淀物主要见于远侧部细胞的细胞质上，而在中间部和神经部则未发现。远侧部大多数对P敏感的细胞与促黄体细胞相同，少数为催乳细胞。这些观察结果表明P在雌性大鼠垂体中促性腺激素的产生和分泌调节中起作用。
