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评价慢性中心性浆液性脉络膜视网膜病变患者经阈下黄色激光治疗后的脉络膜血流指数。

Evaluation of the choroidal vascularity index after subthreshold yellow laser treatment in the patients with chronic central serous chorioretinopathy.

机构信息

Ophthalmology Department, Mugla Education and Training Hospital, Muğla, Turkey.

Ophthalmology Department, Mugla Sitki Kocman University, Mugla, Turkey.

出版信息

Eye (Lond). 2022 Sep;36(9):1826-1831. doi: 10.1038/s41433-022-02090-7. Epub 2022 May 13.

Abstract

PURPOSE

To assess the choroidal vascularity index (CVI) after subthreshold laser treatment in patients with central serous chorioretinopathy (CSC).

METHOD

A total of 32 eyes with CSC were included in this study. In group 1, 14 eyes with persistent CSC were treated with the PASCAL (Endpoint Management Software) at 577-nm wavelength and in group 2, 18 eyes without treatment. The luminal area (LA), stromal area (SA), total area of choroid (TA), and CVI were measured by binarization (ImageJ) of optical coherence tomography images. Changes of choroidal structure parameters were evaluated over 3 months.

RESULT

A significant decrease was observed in LA, TA, and CVI at the third month after the laser treatment (p = 0.018, p = 0.024, p = 0.046). The best-corrected visual acuity (BCVA) and choriocapillaris plexus (CCP) flow area values were increased after treatment in group 1 (p < 0.001, p = 0.002). The final subfoveal fluid height, and CVI were lower in group 1 (p = 0.003, p = 0.011). The visual acuity and CCP flow area were higher in group 1 at the third month (p < 0.001, p = 0.003). A positive correlation between the final BCVA and CVI was observed (r = 0.539, p = 0.01).

DISCUSSION

Decreased CVI was observed in CSC eyes after subthreshold yellow laser treatment. The CVI may be a useful index to evaluate the response to treatment.

摘要

目的

评估在中心性浆液性脉络膜视网膜病变(CSC)患者中接受阈下激光治疗后的脉络膜血流指数(CVI)。

方法

本研究共纳入 32 只 CSC 眼。在第 1 组中,14 只持续性 CSC 眼接受 577nm 波长的 PASCAL(终点管理软件)治疗,在第 2 组中,18 只眼未接受治疗。通过光学相干断层扫描图像的二值化(ImageJ)测量管腔面积(LA)、基质面积(SA)、脉络膜总面积(TA)和 CVI。评估 3 个月内脉络膜结构参数的变化。

结果

激光治疗后第 3 个月,LA、TA 和 CVI 均显著下降(p=0.018,p=0.024,p=0.046)。第 1 组治疗后最佳矫正视力(BCVA)和脉络丛血流面积值增加(p<0.001,p=0.002)。第 1 组最终中心凹下液高和 CVI 较低(p=0.003,p=0.011)。第 1 组在第 3 个月时视力和脉络丛血流面积更高(p<0.001,p=0.003)。最终 BCVA 与 CVI 呈正相关(r=0.539,p=0.01)。

讨论

在接受阈下黄激光治疗的 CSC 眼中观察到 CVI 降低。CVI 可能是评估治疗反应的有用指标。

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