Jacobson J, Bertilson S O
J Int Med Res. 1987 Mar-Apr;15(2):89-95. doi: 10.1177/030006058701500205.
Pain after episiotomy and/or perineal/vaginal rupture in childbirth is severe in many patients and in most cases it can be treated with oral analgesics. In this trial the efficacy and side-effect profile of two combination analgesics, paracetamol/codeine and paracetamol/dextropropoxyphene hydrochloride, were compared in post-partum pain after episiotomy and/or rupture of the perineum. Eighty-five patients were analysed for efficacy and 96 were included in an analysis of side-effects. Paracetamol/codeine was shown to give faster and more efficient pain relief while not causing constipation or other troublesome side-effects.
许多产妇在分娩时行会阴切开术和/或会阴/阴道撕裂后会经历剧痛,大多数情况下口服镇痛药即可缓解。在本试验中,对两种复方镇痛药(对乙酰氨基酚/可待因和对乙酰氨基酚/盐酸右丙氧芬)用于会阴切开术和/或会阴撕裂产后疼痛的疗效和副作用进行了比较。85例患者接受了疗效分析,96例纳入副作用分析。结果显示,对乙酰氨基酚/可待因能更快、更有效地缓解疼痛,且不会引起便秘或其他不良副作用。