Department of Computer Science and Engineering, Konkuk University, Seoul, Korea.
Clinical Research Center, Asan Medical Center, Seoul, Korea.
BMC Med Imaging. 2022 May 13;22(1):87. doi: 10.1186/s12880-022-00815-4.
Despite the dramatic increase in the use of medical imaging in various therapeutic fields of clinical trials, the first step of image quality check (image QC), which aims to check whether images are uploaded appropriately according to the predefined rules, is still performed manually by image analysts, which requires a lot of manpower and time.
In this retrospective study, 1669 computed tomography (CT) images with five specific anatomical locations were collected from Asan Medical Center and Kangdong Sacred Heart Hospital. To generate the ground truth, two radiologists reviewed the anatomical locations and presence of contrast enhancement using the collected data. The individual deep learning model is developed through InceptionResNetv2 and transfer learning, and we propose Image Quality Check-Net (Image QC-Net), an ensemble AI model that utilizes it. To evaluate their clinical effectiveness, the overall accuracy and time spent on image quality check of a conventional model and ImageQC-net were compared.
ImageQC-net body part classification showed excellent performance in both internal (precision, 100%; recall, 100% accuracy, 100%) and external verification sets (precision, 99.8%; recovery rate, 99.8%, accuracy, 99.8%). In addition, contrast enhancement classification performance achieved 100% precision, recall, and accuracy in the internal verification set and achieved (precision, 100%; recall, 100%; accuracy 100%) in the external dataset. In the case of clinical effects, the reduction of time by checking the quality of artificial intelligence (AI) support by analysts 1 and 2 (49.7% and 48.3%, respectively) was statistically significant (p < 0.001).
Comprehensive AI techniques to identify body parts and contrast enhancement on CT images are highly accurate and can significantly reduce the time spent on image quality checks.
尽管在临床试验的各个治疗领域中,医学影像的使用急剧增加,但旨在根据预定义规则检查图像是否已正确上传的图像质量检查(image QC)的第一步仍然由图像分析师手动完成,这需要大量的人力和时间。
在这项回顾性研究中,从 Asan 医疗中心和 Kangdong 圣心医院收集了 1669 张具有五个特定解剖位置的计算机断层扫描(CT)图像。为了生成真实情况,两名放射科医生使用收集的数据检查了解剖位置和对比度增强的存在情况。通过 InceptionResNetv2 和迁移学习开发了个体深度学习模型,并提出了利用该模型的图像质量检查网络(Image QC-Net)。为了评估其临床效果,比较了传统模型和 ImageQC-net 对图像质量检查的总准确性和所花费的时间。
ImageQC-net 身体部位分类在内部(准确率 100%,召回率 100%,准确率 100%)和外部验证集(准确率 99.8%,恢复率 99.8%,准确率 99.8%)中均表现出优异的性能。此外,内部验证集的对比度增强分类性能达到了 100%的准确率、召回率和准确性,外部数据集的准确率为 100%、召回率为 100%、准确率为 100%。在临床效果方面,分析师 1 和 2 检查人工智能(AI)支持的质量时,时间减少(分别为 49.7%和 48.3%)具有统计学意义(p<0.001)。
用于识别 CT 图像的身体部位和对比度增强的综合 AI 技术具有很高的准确性,并可以大大减少图像质量检查所花费的时间。