Chen Hao, Wang Chunjie, Huasai Simujide, Chen Aorigele
College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot 010018, China.
Animals (Basel). 2022 Apr 29;12(9):1147. doi: 10.3390/ani12091147.
The diet energy level plays a vital role in the energy balance of transition cows. We investigated the effects of high dietary energy density on body metabolism. Twenty multiparous Angus cows were randomly assigned to two treatment groups (10 cows/treatment), one receiving a high-energy (HE) diet (NEm = 1.67 Mcal/kg of DM) and the other administered a control (CON) diet (NEm = 1.53 Mcal/kg of DM). The results indicated that feeding a high-energy diet resulted in higher plasma glucose concentration and lower concentrations of plasma NEFA and BHBA on d 14 relative to calving in the HE-fed cows compared to the CON-fed ones. The postpartum plasma levels of T-AOC were lower in cows that received the CON diet than in cows in the HE group, while the concentration of malondialdehyde (MDA) showed an opposite trend. Among the 51 significantly different metabolites, the concentrations of most identified fatty acids decreased in HE cows. The concentrations of inosine, glutamine, and citric acid were higher in HE-fed cows than in CON-fed cows. Enrichment analysis revealed that linoleic acid metabolism, valine, leucine as well as isoleucine biosynthesis, and glycerophospholipid metabolism were significantly enriched in the two groups.
日粮能量水平在围产母牛的能量平衡中起着至关重要的作用。我们研究了高日粮能量密度对机体代谢的影响。将20头经产安格斯母牛随机分为两个处理组（每组10头），一组饲喂高能量（HE）日粮（产奶净能=1.67兆卡/千克干物质），另一组饲喂对照（CON）日粮（产奶净能=1.53兆卡/千克干物质）。结果表明，与CON组相比，HE组母牛在产后第14天饲喂高能量日粮导致血浆葡萄糖浓度更高，血浆非酯化脂肪酸和β-羟基丁酸浓度更低。CON组母牛产后血浆总抗氧化能力水平低于HE组母牛，而丙二醛（MDA）浓度则呈现相反趋势。在51种差异显著的代谢产物中，大多数已鉴定脂肪酸的浓度在HE组母牛中降低。HE组母牛中肌苷、谷氨酰胺和柠檬酸的浓度高于CON组母牛。富集分析表明，两组中均显著富集了亚油酸代谢、缬氨酸、亮氨酸和异亮氨酸生物合成以及甘油磷脂代谢。
