Jeon Yong-Sung, Kim Yoo-Bhin, Lee Hyun-Gwan, Park Jina, Heo Yun-Ji, Chu Gyo-Moon, Lee Kyung-Woo
Department of Animal Science and Technology, Konkuk University, 120 Neungdong-ro, Gwangjin-gu, Seoul 05029, Korea.
Busanbio, Nonghyup Feed Co., Ltd., 337 Uam-ro, Nam-gu, Busan 48475, Korea.
Animals (Basel). 2022 May 6;12(9):1200. doi: 10.3390/ani12091200.
The objective of this study was to evaluate the effects of dietary sulfur from either organic (methyl sulfonyl methane, MSM) or inorganic (sodium sulfate, SS) sources on the growth performance of broiler chickens challenged against a high-dose coccidiosis vaccine. A total of 320 day-old Ross 308 broiler chicks were randomly placed into 32 pens of 10 birds each (keeping 16 pens/control group and 8 pens/treatment group until 21 days post-hatch) and reared for 28 days. The experimental diets were formulated by mixing a corn and soybean meal-based control diet with MSM or SS. At 21 days post-hatch, half ( = 8) of the control and all of the sulfur-added diet-fed (i.e., MSM and SS) groups were challenged with a 30-fold dose of a commercially available vaccine (Livacox T coccidiosis vaccine). Unchallenged control chicks ( = 8) were considered as the negative control group. At 21 days (before coccidiosis vaccine challenge), the production parameters and cecal short-chain fatty acids were not affected by dietary treatments. The concentrations of total antioxidant capacity in liver samples were elevated in both the MSM and SS groups compared with the control group ( = 0.001). During 21 to 28 days (i.e., one week post coccidiosis vaccine challenge), challenge tended to lower body weight and feed intake by an average of 5.3% ( = 0.262) and 2.8% ( = 0.504), respectively, but to increase the feed conversion ratio by an average of 2.7% ( = 0.087) compared with the non-challenged control groups. None of dietary sulfur groups affected the body weight gain, feed intake, or feed conversion ratio of vaccine-challenged chickens. Mild -specific lesions were noted in duodenum ( = 0.006), jejunum ( = 0.017), and ceca ( = 0.047), but dietary sulfur treatments did not affect the -induced gut lesion scores. At 28 days, challenge significantly impaired ( = 0.001) the apparent ileal digestibility of crude protein and crude ash compared with the naïve control group. Dietary MSM increased the apparent ileal digestibility of crude ash by 15.5% on average compared with the coccidiosis vaccine control group. We conclude that dietary antioxidant sulfur of organic or inorganic origins at the inclusion level (i.e., 0.7 g sulfur/kg of diet) has a limited effect on the growth performance of chickens challenged with coccidiosis vaccine.
本研究的目的是评估来自有机（甲基磺酰甲烷，MSM）或无机（硫酸钠，SS）来源的膳食硫对接受高剂量球虫病疫苗攻击的肉鸡生长性能的影响。总共320只1日龄的罗斯308肉鸡雏鸡被随机放入32个围栏中，每个围栏10只鸡（孵化后21天内每组保持16个围栏/对照组和8个围栏/处理组），饲养28天。实验日粮是通过将基于玉米和豆粕的对照日粮与MSM或SS混合配制而成。在孵化后21天，对照组的一半（ = 8）和所有添加硫的日粮组（即MSM和SS）用市售疫苗（Livacox T球虫病疫苗）30倍剂量进行攻击。未受攻击的对照雏鸡（ = 8）被视为阴性对照组。在21天（球虫病疫苗攻击前），生产参数和盲肠短链脂肪酸不受日粮处理的影响。与对照组相比，MSM和SS组肝脏样本中的总抗氧化能力浓度均升高（ = 0.001）。在21至28天期间（即球虫病疫苗攻击后一周），与未受攻击的对照组相比，攻击倾向于使体重和采食量分别平均降低5.3%（ = 0.262）和2.8%（ = 0.504），但使饲料转化率平均提高2.7%（ = 0.087）。日粮硫组均未影响疫苗攻击鸡的体重增加、采食量或饲料转化率。在十二指肠（ = 0.006）、空肠（ = 0.017）和盲肠（ = 0.047）中观察到轻度特异性病变，但日粮硫处理未影响球虫病诱导的肠道病变评分。在28天时，与未感染对照组相比，球虫病攻击显著损害（ = 0.001）了粗蛋白和粗灰分的回肠表观消化率。与球虫病疫苗对照组相比，日粮MSM平均使粗灰分的回肠表观消化率提高了15.5%。我们得出结论，日粮中有机或无机来源的抗氧化硫（即0.7克硫/千克日粮）对接受球虫病疫苗攻击的鸡的生长性能影响有限。
