Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao 266071, China.
Nutrients. 2022 Apr 24;14(9):1783. doi: 10.3390/nu14091783.
Background: No longitudinal studies have explored the relationship between tri-ponderal mass index (TMI) and blood pressure (BP) in children. This study is aimed to investigate the temporal associations between TMI and BP among children in China. Methods: A longitudinal study was carried out with Chinese children from 2014 to 2019. Data of the anthropometric examination and blood pressure were collected annually. TMI was calculated by dividing weight by the cube of height. BP was measured using a standard mercury sphygmomanometer. We investigated temporal associations between TMI and BP with a cross-lagged panel model using repeated measure data from 2014 (Wave 1), 2016 (Wave 2), and 2018 (Wave 3). Results: Results of the cross-lagged panel model showed that TMI was associated with subsequent BP. Participants with higher levels of TMI presented higher levels of BP (Wave 1: β = 0.737 for systolic blood pressure (SBP) and β = 0.308 for diastolic blood pressure (DBP), Wave 2: β = 0.422 for SBP and β = 0.165 for DBP, p < 0.01). In addition, children with higher BP could also present higher TMI (Wave 1: β = 0.004 for SBP and β = 0.006 for DBP, Wave 2: β = 0.003 for SBP and β = 0.005 for DBP, p < 0.01), but the cross-lag path coefficient indicated that the influence of TMI on BP was stronger than the influence of BP on TMI. Conclusions: There was a temporal association between TMI and BP in Chinese children. Higher TMI predicted higher subsequent BP rather than the reverse relationship.
目前尚无研究探讨三重点体重指数（TMI）与儿童血压（BP）之间的关系。本研究旨在探讨中国儿童中 TMI 与 BP 之间的时间关联。
这是一项在中国儿童中进行的纵向研究。从 2014 年至 2019 年，每年收集体格检查和血压数据。TMI 通过体重除以身高的立方计算得出。使用标准的水银血压计测量血压。我们使用重复测量数据的交叉滞后面板模型，从 2014 年（第 1 波）、2016 年（第 2 波）和 2018 年（第 3 波），调查了 TMI 与 BP 之间的时间关联。
交叉滞后面板模型的结果表明，TMI 与随后的 BP 相关。TMI 水平较高的参与者血压水平较高（第 1 波：收缩压（SBP）的β=0.737，舒张压（DBP）的β=0.308，第 2 波：SBP 的β=0.422，DBP 的β=0.165，均<0.01）。此外，血压较高的儿童也可能表现出较高的 TMI（第 1 波：SBP 的β=0.004，DBP 的β=0.006，第 2 波：SBP 的β=0.003，DBP 的β=0.005，均<0.01），但交叉滞后路径系数表明，TMI 对 BP 的影响强于 BP 对 TMI 的影响。
中国儿童的 TMI 与 BP 之间存在时间关联。较高的 TMI 预测随后的 BP 较高，而不是相反的关系。
