Córdoba-Fernández Antonio, Lobo-Martín Adrián
Departamento de Podología, Universidad de Sevilla, C/Avicena s/n, 41009 Sevilla, Spain.
J Clin Med. 2022 Apr 26;11(9):2420. doi: 10.3390/jcm11092420.
Background: Some studies have recommended combining germinal matrix excision with phenol ablation in the treatment of onychocryptosis. Matrixectomy after phenolization has been shown to be an effective modification to reduce the drawbacks associated with phenolization alone, although it increases the risk of minor postoperative bleeding. The present study aims to assess the effectiveness and safety of gelatin sponges as hemostatic agents in partial matrixectomy after phenolization. Methods: A comparative clinical trial in parallel groups was designed in 74 halluces (44 patients) with stage I, II, and III onychocryptosis. All participants were randomly assigned to 3 groups: Group A (control group), Group B (conventional gelatin sponge), and Group C (high porosity gelatin sponge). Results: The quantified mean blood loss in the first 48 h after surgery in patients in both experimental groups was significantly lower compared to the control group. The lowest mean blood loss was recorded in Group C (p < 0.001) and followed by Group B (p = 0.005). No adverse effects were recorded in any of the patients included in the experimental groups. Conclusions: Hemostatic gelatin sponges were demonstrated to be effective and safe devices for the control of minor postoperative bleeding associated with matrixectomy after segmental phenolization.
一些研究建议在治疗嵌甲症时将生发基质切除术与苯酚消融术相结合。苯酚处理后进行基质切除术已被证明是一种有效的改良方法，可减少单独使用苯酚处理的缺点，尽管这会增加术后轻微出血的风险。本研究旨在评估明胶海绵作为苯酚处理后部分基质切除术中止血剂的有效性和安全性。方法：对74例患有I、II和III期嵌甲症的拇趾（44例患者）进行了平行组比较临床试验。所有参与者被随机分为3组：A组（对照组）、B组（传统明胶海绵组）和C组（高孔隙率明胶海绵组）。结果：与对照组相比，两个实验组患者术后48小时内的量化平均失血量显著降低。C组的平均失血量最低（p < 0.001），其次是B组（p = 0.005）。实验组的任何患者均未记录到不良反应。结论：止血明胶海绵被证明是控制节段性苯酚处理后基质切除术后轻微术后出血的有效且安全的装置。
