Grigore Mihaela, Vasilache Ingrid-Andrada, Cianga Petru, Constantinescu Daniela, Duma Odetta, Matasariu Roxana Daniela, Scripcariu Ioana-Sadiye
Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Department of Immunology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
J Clin Med. 2022 Apr 29;11(9):2503. doi: 10.3390/jcm11092503.
(1) Background: Low patient’s adherence to conventional cervical cancer screening methods determined the need to take into consideration alternative approaches, and vaginal HPV self-sampling is one of them. We aimed to evaluate, using an online survey, the Romanian women’s acceptability of vaginal HPV self-sampling. (2) Methods: A 13-questions online survey was distributed on three Facebook groups, and the results were summarized. (3) Results: Despite of good educational background, 10.8% (n = 60) of the respondents did not know what a Pap smear is, and 33% (n = 183) were not informed about the free national cervical cancer screening program. Multivariate analysis revealed an increased likelihood of vaginal self-sampling acceptance among respondents who did not know about Pap test (OR: 7.80; 95%CI: 1.062−57.431; p = 0.021), national cervical cancer screening program (OR: 1.96; 95%CI: 1.010−3.806; p = 0.02), HPV infection (OR: 7.35; 95%CI: 3.099−17.449; p< 0.001) or HPV test (OR: 1.67; 95%CI: 0.950−2.948; p = 0.03). Moreover, women who did not previously undergo a cervical cancer screening program were more likely to accept the new screening method (OR: 1.62; 95%CI: 0.878−3.015; p = 0.04). (4) Conclusions: Our results showed high acceptability rates of vaginal HPV self-sampling among participants.
（1）背景：患者对传统宫颈癌筛查方法的依从性较低，因此需要考虑其他替代方法，阴道人乳头瘤病毒（HPV）自我采样就是其中之一。我们旨在通过在线调查评估罗马尼亚女性对阴道HPV自我采样的接受度。（2）方法：在三个脸书群组中开展了一项包含13个问题的在线调查，并对结果进行了总结。（3）结果：尽管受访者教育背景良好，但仍有10.8%（n = 60）的人不知道巴氏涂片检查是什么，33%（n = 183）的人未听说过国家免费宫颈癌筛查项目。多因素分析显示，对巴氏试验不了解的受访者接受阴道自我采样的可能性增加（比值比：7.80；95%置信区间：1.062 - 57.431；p = 0.021），对国家宫颈癌筛查项目不了解的受访者接受阴道自我采样的可能性增加（比值比：1.96；95%置信区间：1.010 - 3.806；p = 0.02），感染HPV的受访者接受阴道自我采样的可能性增加（比值比：7.35；95%置信区间：3.099 - 17.449；p < 0.001），对HPV检测不了解的受访者接受阴道自我采样的可能性增加（比值比：1.67；95%置信区间：0.950 - 2.948；p = 0.03）。此外，之前未参加过宫颈癌筛查项目的女性更有可能接受新的筛查方法（比值比：1.62；95%置信区间：0.878 - 3.015；p = 0.04）。（4）结论：我们的结果显示参与者对阴道HPV自我采样的接受率较高。
