Mocan Mihaela, Szabo Robert, Constantinescu Cătălin, Cucoreanu Ciprian, Chira Romeo Ioan
Department of Internal Medicine, University of Medicine and Pharmacy "Iuliu Hatieganu", 400012 Cluj-Napoca, Romania.
Department of Internal Medicine, Emergency County Hospital Cluj, Cluj-Napoca 400006, Romania.
J Clin Med. 2022 May 2;11(9):2554. doi: 10.3390/jcm11092554.
SARS-CoV-2 infection (COVID-19) affects the respiratory system but is not limited to it. The gastrointestinal symptoms are polymorphic, including diarrhea, vomiting, abdominal pain, and even acute pancreatitis (AP). Pregnant women are more vulnerable to SARS-CoV-2 infection and have a higher risk of severe outcomes of COVID-19.
We present a case report of a 31-year-old primigravid patient at 30 weeks of gestation, unvaccinated, with a medical history of thrombophilia, chronic nephropathy of unknown origin, hypertension, and optic neuropathy with left eye hemianopsia. She was diagnosed with moderate-to-severe COVID-19 and respiratory failure, with indication for cesarean section. Postpartum, she developed severe acute pancreatitis, complicated by peripancreatic and supradiaphragmatic abscesses. After 3 months of hospitalization and eight surgical interventions, the patient was discharged. A short mini-review of the literature is introduced.
Pregnant women with cardiovascular comorbidities are prone to severe complications of SARS-CoV-2 infection. Clinicians should be aware of the association of SARS-CoV-2 and AP in pregnant women.
严重急性呼吸综合征冠状病毒2感染（COVID-19）会影响呼吸系统，但不仅限于此。胃肠道症状多种多样，包括腹泻、呕吐、腹痛，甚至急性胰腺炎（AP）。孕妇更容易感染严重急性呼吸综合征冠状病毒2，且发生COVID-19严重后果的风险更高。
我们报告一例31岁初产妇，妊娠30周，未接种疫苗，有血栓形成倾向、不明原因慢性肾病、高血压病史，以及左眼偏盲的视神经病变。她被诊断为中度至重度COVID-19和呼吸衰竭，有剖宫产指征。产后，她发生了严重急性胰腺炎，并伴有胰周和膈上脓肿。经过3个月的住院治疗和8次手术干预后，患者出院。本文还对相关文献进行了简短的综述。
患有心血管合并症的孕妇容易发生严重急性呼吸综合征冠状病毒2感染的并发症。临床医生应了解严重急性呼吸综合征冠状病毒2与孕妇急性胰腺炎之间的关联。
