Department of Medicine, Guthrie Robert Packer Hospital, Sayre, PA.
Clinical Pharmacy Specialist, PGY1 Pharmacy Residency Program Director, Guthrie Robert Packer Hospital, Sayre, PA; and.
Am J Ther. 2022 Jul 1;29(4):e444-e446. doi: 10.1097/MJT.0000000000001266.
We report a case of acute pancreatitis that developed after four days of remdesivir therapy in a patient being treated for COVID-19. Despite improvement in patient's respiratory status, abdominal pain worsened and clinical signs and symptoms progressed to a diagnosis of acute pancreatitis 4 days after initiation of remdesivir therapy. Withdrawal of remdesivir paired with medical management of acute pancreatitis led to the resolution of pancreatitis within three days. To our knowledge, this is the first case report depicting remdesivir as a possible cause of acute pancreatitis.
我们报告了一例 COVID-19 患者在接受瑞德西韦治疗四天后发生的急性胰腺炎。尽管患者的呼吸状况有所改善，但腹痛加重，临床症状和体征进展为急性胰腺炎，在开始瑞德西韦治疗四天后确诊。停用瑞德西韦并对急性胰腺炎进行医学治疗，导致胰腺炎在三天内得到缓解。据我们所知，这是首例描述瑞德西韦可能导致急性胰腺炎的病例报告。
