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65岁以上手术患者髋部骨折6个月时中度或重度认知障碍的预测因素

Predictors of Moderate or Severe Cognitive Impairment at Six Months of the Hip Fracture in the Surgical Patient over 65 Years of Age.

作者信息

González-Marcos Enrique, González-García Enrique, Rodríguez-Fernández Paula, González-Bernal Jerónimo J, Sánchez-González Esteban, González-Santos Josefa

机构信息

RACA 11 Artillery Regiment, Cid Campeador Military Base, 09193 Burgos, Spain.

Traumatology and Orthopedic Surgery Service, Burgos University Hospital, 09006 Burgos, Spain.

出版信息

J Clin Med. 2022 May 6;11(9):2608. doi: 10.3390/jcm11092608.

DOI:10.3390/jcm11092608
PMID:35566734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9101953/
Abstract

BACKGROUND

cognitive impairment is known to be very common in patients with hip fractures, but studies are needed to help understand the relationship between both events. Our goal was to determine the relationship between moderate or severe cognitive impairment and hip fractures during the six months following that episode.

METHODS

a retrospective longitudinal study was conducted on a sample of 665 people over 65 years of age. The main variable of the study was cognitive impairment at six months of fracture, assessed using the Pfeiffer scale (PS). Other data related to clinical features were also collected for further analysis.

RESULTS

binary logistic regression analyses showed that the main factors related to moderate or severe cognitive impairment at the sixth month of the fracture were age (OR = 1.078), initial cognitive impairment (OR = 535.762), and discharge (OR = 547.91), cognitive worsening at the sixth month with respect to the time of admission (OR = 7.024), moderate dependence on admission (OR = 15.474) and at six months (OR = 8.088), poor ambulation at discharge (OR = 5.071) and institutionalization prior to admission (OR = 5.349) or during the first semester after fracture (OR = 6.317).

CONCLUSIONS

this research provides evidence about the clinical factors that predict moderate or severe cognitive decline at the sixth month in patients undergoing surgery for a hip fracture.

摘要

背景

认知障碍在髋部骨折患者中非常常见,但仍需要开展研究以帮助理解这两种情况之间的关系。我们的目标是确定在髋部骨折事件发生后的六个月内,中度或重度认知障碍与髋部骨折之间的关系。

方法

对665名65岁以上的人群进行了一项回顾性纵向研究。该研究的主要变量是骨折六个月时的认知障碍,采用 Pfeiffer 量表(PS)进行评估。还收集了与临床特征相关的其他数据以进行进一步分析。

结果

二元逻辑回归分析表明,与骨折后第六个月出现中度或重度认知障碍相关的主要因素包括年龄(比值比[OR]=1.078)、初始认知障碍(OR=535.762)、出院(OR=547.91)、与入院时相比第六个月认知功能恶化(OR=7.024)、入院时中度依赖(OR=15.474)和六个月时(OR=8.088)、出院时行走能力差(OR=5.071)以及入院前(OR=5.349)或骨折后第一学期内(OR=6.317)入住机构。

结论

本研究为预测髋部骨折手术患者在第六个月出现中度或重度认知衰退的临床因素提供了证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a3/9101953/59714cdf2bf7/jcm-11-02608-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a3/9101953/59714cdf2bf7/jcm-11-02608-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90a3/9101953/59714cdf2bf7/jcm-11-02608-g001.jpg

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Int J Geriatr Psychiatry. 2021 Jul;36(7):993-1003. doi: 10.1002/gps.5508. Epub 2021 Feb 27.
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Changes in Health-Related Quality of Life for Older Persons With Cognitive Impairment After Hip Fracture Surgery: A Systematic Review.老年人髋部骨折手术后认知障碍相关健康相关生活质量的变化:系统评价。
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