Keith W J, Greville K A
Ear Hear. 1987 Feb;8(1):49-55. doi: 10.1097/00003446-198702000-00009.
Evidence reported in the literature indicates that wave I of the auditory brain stem response is influenced by cochlear contributions from a more basal area of the cochlea than is wave V. This phenomenon is invoked to explain different latency-intensity function patterns of waves I and V and the I-V interval for four types of cochlear hearing loss. In high frequency hearing losses wave V is delayed at low intensities. Wave I tends to be delayed at all intensities and by a greater amount than wave V. The I-V interval is often reduced with the effect maximal at higher intensities. Low frequency hearing losses tend to cause early wave V latencies at low intensities. Wave I latencies are normal. The I-V interval is therefore reduced at lower intensities. Flat hearing losses produce normal latency-intensity functions. High frequency notched audiograms are almost always associated with delayed wave V but early wave I latencies. The I-V interval is therefore significantly prolonged with the effect maximal at low intensities. The variability of the I-V interval as a function of audiometric configuration indicates that it is not a pure measure of central conduction time.
文献报道的证据表明，听觉脑干反应的波I比波V受耳蜗更基部区域的耳蜗贡献影响更大。这一现象被用来解释波I和波V的不同潜伏期 - 强度函数模式以及四种类型的耳蜗性听力损失的I - V间期。在高频听力损失中，波V在低强度时延迟。波I在所有强度下往往都会延迟，且比波V延迟的幅度更大。I - V间期通常会缩短，在较高强度时效果最大。低频听力损失往往会在低强度时导致波V潜伏期提前。波I潜伏期正常。因此，I - V间期在较低强度时缩短。平坦型听力损失产生正常的潜伏期 - 强度函数。高频切迹听力图几乎总是与波V延迟但波I潜伏期提前相关。因此，I - V间期显著延长，在低强度时效果最大。I - V间期作为听力测定配置函数的变异性表明，它不是中央传导时间的纯粹测量指标。
