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采用基于单中心数据的杂交技术开通血栓形成的维持性血液透析动静脉瘘内血栓

Recanalization of thrombosed aneurysmal hemodialysis arterovenous fistulas using a hybrid technique based on data from a single center.

机构信息

Department of Nephropathy, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, P.R. China.

Department of Nephropathy, Anqing Municipal Hospital, Anqing, Anhui, 246000, P.R. China.

出版信息

BMC Nephrol. 2022 May 14;23(1):185. doi: 10.1186/s12882-022-02820-9.

Abstract

OBJECTIVE

To explore the technical specifications and clinical outcomes of thrombosed aneurysmal haemodialysis arteriovenous fistula (AVF) treated with ultrasound-guided percutaneous transluminal angioplasty combined with minimal aneurysmotomy.

METHODS

This case series study included 11 patients who had thrombosed aneurysmal AVF and underwent salvage procedures over a 13-month period. All procedures were performed under duplex guidance. Minimal aneurysmotomy was performed, along with manual thrombectomy and thrombolytic agent infusion, followed by angioplasty to macerate the thrombus and sufficiently dilate potential stenoses. A successful procedure was defined as immediate restoration of flow through the AVF.

RESULTS

The 11 patients (four males and seven females) had a mean age of 49.6 years ± 11.9 years. Six patients (54.5%) had two or more aneurysms. The mean aneurysm maximal diameter was 21.5 mm (standard deviation: ± 5.0 mm), and the mean thrombus length was 12.9 cm (8-22 cm). Ten (83.3%) of the 12 procedures were technically successful. The mean duration of operation was 150.9 minutes (standard deviation: ± 34.2 minutes), and mean postoperative AVF blood flow was 728.6 ml/min (standard deviation: ± 53.7 mi/min). The resumption of hemodialysis was successful in all 11 cases, with a clinical success rate of 100%. The primary patency rates were 90.0% and 75.0% at three and four months over a mean follow-up time of 6.3 months (3-12 months). The secondary patency rates were 90.4% at three and four months.

CONCLUSION

A hybrid approach combining ultrasound-guided percutaneous transluminal angioplasty and minimal aneurysmotomy might be a safe and effective method for thrombosed aneurysmal AVF salvage.

摘要

目的

探讨超声引导下经皮腔内血管成形术联合最小化动脉瘤切开术治疗血栓形成的动静脉瘘(AVF)的技术规范和临床效果。

方法

本病例系列研究纳入了 11 例在 13 个月内接受挽救性手术治疗的血栓形成的动静脉瘘患者。所有手术均在双功能超声引导下进行。采用最小化动脉瘤切开术,联合手动血栓切除术和溶栓药物灌注,然后进行血管成形术以软化血栓并充分扩张潜在狭窄部位。成功的手术定义为即刻恢复 AVF 的血流。

结果

11 例患者(4 名男性和 7 名女性)平均年龄为 49.6 岁±11.9 岁。6 例(54.5%)患者有两个或更多动脉瘤。最大动脉瘤直径平均为 21.5 毫米(标准差:±5.0 毫米),血栓长度平均为 12.9 厘米(8-22 厘米)。12 例手术中 10 例(83.3%)技术上成功。手术平均时间为 150.9 分钟(标准差:±34.2 分钟),术后平均 AVF 血流为 728.6ml/min(标准差:±53.7ml/min)。11 例患者均成功恢复血液透析,临床成功率为 100%。平均随访 6.3 个月(3-12 个月)时,3 个月和 4 个月时的一期通畅率分别为 90.0%和 75.0%。3 个月和 4 个月时的二期通畅率分别为 90.4%。

结论

超声引导下经皮腔内血管成形术联合最小化动脉瘤切开术可能是治疗血栓形成的动静脉瘘的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b41f/9107707/80d649ef67ef/12882_2022_2820_Fig1_HTML.jpg

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