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经皮超声引导溶栓注射:一种有前途的抢救血栓形成的自体血液透析瘘的方法。

A promising method for the salvage of thrombosed native hemodialysis fistulas: percutaneous ultrasound-guided thrombolytic injection.

机构信息

Department of Radiology, Dışkapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Ankara, Turkey

出版信息

Turk J Med Sci. 2019 Jul 4;49(4):1179-1184. doi: 10.3906/sag-1902-206.

Abstract

BACKGROUND/AIM: It was aimed to describe the technical aspects and outcomes of percutaneous ultrasound-guided recanalization of thrombosed hemodialysis fistulas by thrombolytic injection.

MATERIALS AND METHODS

A retrospective review was performed on patients with thrombosed native hemodialysis fistula who were treated using the percutaneous ultrasound-guided thrombolytic agent injection technique at the interventional radiology department. A total of 17 patients [7 women (41.2%) and 10 men (58.8%)] were included in this study. All of the data, including demographic information and clinical findings, were obtained from the patients’ medical records and follow-up form of the procedure.

RESULTS

The mean fistula age was 5.6 years (range: 1–15 years). The mean diameter of the thrombosed segment was 5.53 cm (2–10 cm). Localization of the thrombi was in the aneurysmal segment at the level of needle insertion in 64.7% (n: 11) of patients, while it was on the venous side of the anastomosis in 35.3% (n: 6). The mean dose of tissue plasminogen activator (tPA) used in all of the sessions was 8.88 mg (5–17 mg). Overall technical success after all of the administrations was 100% and clinical success was 94.1%.

CONCLUSION

Percutaneous ultrasound-guided thrombolytic injection in native hemodialysis fistulas is a rapid, practical, repeatable treatment method that is received on an outpatient basis with low risk of bleeding, and prevents unnecessary endovascular interventions or surgical operations.

摘要

背景/目的:旨在描述经皮超声引导溶栓注射治疗血栓形成的血液透析瘘的技术方面和结果。

材料和方法

回顾性分析了在介入放射科采用经皮超声引导溶栓药物注射技术治疗血栓形成的自体血液透析瘘患者。本研究共纳入 17 例患者[7 名女性(41.2%)和 10 名男性(58.8%)]。所有数据,包括人口统计学信息和临床发现,均从患者的病历和程序随访表中获得。

结果

瘘管平均年龄为 5.6 岁(范围:1-15 岁)。血栓形成段的平均直径为 5.53cm(2-10cm)。血栓的定位在 64.7%(n:11)的患者中位于针插入水平的动脉瘤段,而在 35.3%(n:6)的患者中位于吻合静脉侧。所有治疗中使用的组织型纤溶酶原激活剂(tPA)的平均剂量为 8.88mg(5-17mg)。所有治疗后的总技术成功率为 100%,临床成功率为 94.1%。

结论

经皮超声引导溶栓注射治疗自体血液透析瘘是一种快速、实用、可重复的治疗方法,可在门诊进行,出血风险低,可预防不必要的血管内介入或手术操作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7631/7018234/a3ed3530ef69/turkjmedsci-49-1179-fig001.jpg

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