Department of Endocrinology, The First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.
Department of Endocrinology, Fujian Provincial Hospital, Key Laboratory of Endocrinology, Fujian Medical University, Fuzhou, Fujian 350001, China.
Chin Med J (Engl). 2022 May 20;135(10):1242-1248. doi: 10.1097/CM9.0000000000001835.
Inadequate sleep duration is associated with a higher risk of type 2 diabetes and the relationship is nonlinear. We aim to assess the curve relationship between night sleep duration and the incidence of type 2 diabetes in China.
A cohort of 11,539 participants from the REACTION study without diabetes at baseline (2011) were followed until 2014 for the development of type 2 diabetes. The average number of hours of sleep per night was grouped. Incidence rates and odds ratios (ORs) were calculated for the development of diabetes in each sleep duration category.
Compared to people who sleep for 7 to 8 h/night, people with longer sleep duration (≥9 h/night) had a greater risk of type 2 diabetes (OR: 1.27; 95% CI: 1.01-1.61), while shorter sleep (<6 h/night) had no significant difference in risk of type 2 diabetes. When the dataset was stratified based on selected covariates, the association between type 2 diabetes and long sleep duration became more evident among individuals <65 years of age, male, body mass index <24 kg/m 2 or with hypertension or hyperlipidemia, no interaction effects were observed. Furthermore, compared to people persistently sleeping 7 to 9 h/night, those who persistently slept ≥9 h/night had a higher risk of type 2 diabetes. The optimal sleep duration was 6.3 to 7.5 h/night.
Short or long sleep duration was associated with a higher risk of type 2 diabetes. Persistently long sleep duration increased the risk.
睡眠不足与 2 型糖尿病的风险增加有关，且这种关系是非线性的。我们旨在评估夜间睡眠时间与中国 2 型糖尿病发病之间的曲线关系。
REACTION 研究中的一个队列包括 11539 名基线时（2011 年）无糖尿病的参与者，随访至 2014 年以观察 2 型糖尿病的发生情况。将每晚平均睡眠时间分为不同组别。计算每个睡眠时间组别的糖尿病发病率和比值比（OR）。
与每晚睡眠 7 至 8 小时的人相比，睡眠时间较长（≥9 小时/晚）的人患 2 型糖尿病的风险更高（OR：1.27；95%CI：1.01-1.61），而睡眠时间较短（<6 小时/晚）的人患 2 型糖尿病的风险无显著差异。当根据选定的协变量对数据集进行分层时，睡眠时间与 2 型糖尿病之间的关联在年龄<65 岁、男性、体重指数<24kg/m 2 或患有高血压或高血脂、无交互作用的个体中变得更加明显。此外，与持续睡眠时间为 7 至 9 小时/晚的人相比，持续睡眠时间≥9 小时/晚的人患 2 型糖尿病的风险更高。最佳睡眠时间为 6.3 至 7.5 小时/晚。
短或长的睡眠时间与 2 型糖尿病的风险增加有关。持续长时间的睡眠会增加风险。
