Li Jinxi, Lu Yiduo, Zhang Xuyun, Liu Gang
International Medical College, Chongqing Medical University, Chongqing, People's Republic of China.
College of Basic Medical Sciences, Naval Medical University, Shanghai, People's Republic of China.
Nat Sci Sleep. 2024 Jul 31;16:1121-1130. doi: 10.2147/NSS.S466283. eCollection 2024.
The burden of cardiometabolic diseases (CMDs), defined as stroke, coronary artery disease, and diabetes mellitus, continues to pose a global challenge. Sleep duration has been linked to cardiovascular health. However, there is a lack of focused investigations on CMDs in underdeveloped areas of China.
This study aimed to examine the relationship between sleep duration and CMDs among residents from southwest China.
This large cross-sectional study screened data from the National Key Research and Development Program (2018YFC1311400). Based on sleep duration reported through a standardized questionnaire, encompassing the sleep patterns of the past five years, participants were classified into three groups: <6, 6-8, >8 hours. Baseline characteristics were compared, and Poisson regression models were used to assess the relationship between sleep duration and CMDs. Subgroup analysis was conducted based on age and gender.
This study included 28,908 participants with an average age of 65.6 ± 10.0 years, of whom 57.6% were female. The overall prevalence of CMDs was 22.6%. After multivariate adjustments, the prevalence ratios (PR) (95% CI) for CMDs across the three groups (6-8h, <6h and >8h) were: reference, 1.140 (1.068-1.218), 1.060 (0.961-1.169) ( =0.003), respectively. The subgroup analysis revealed that among older females, a longer sleep duration (>8h) was also associated with an increased prevalence risk of CMDs, with PR 1.169 (1.001-1.365) (=0.049).
A shorter sleep duration (<6 hours) was associated with an increased risk of CMDs in the general population, while a longer sleep duration (>8 hours) also raised the prevalence risk among older females.
心血管代谢疾病（CMDs）包括中风、冠状动脉疾病和糖尿病，其负担持续给全球带来挑战。睡眠时间与心血管健康有关。然而，中国欠发达地区缺乏对心血管代谢疾病的重点研究。
本研究旨在探讨中国西南地区居民睡眠时间与心血管代谢疾病之间的关系。
这项大型横断面研究筛选了国家重点研发计划（2018YFC1311400）的数据。根据通过标准化问卷报告的睡眠时间，涵盖过去五年的睡眠模式，参与者被分为三组：<6小时、6 - 8小时、>8小时。比较了基线特征，并使用泊松回归模型评估睡眠时间与心血管代谢疾病之间的关系。根据年龄和性别进行了亚组分析。
本研究纳入了28908名参与者，平均年龄为65.6±10.0岁，其中57.6%为女性。心血管代谢疾病的总体患病率为22.6%。经过多变量调整后，三组（6 - 8小时、<6小时和>8小时）心血管代谢疾病的患病率比值（PR）（95%CI）分别为：参照组、1.140（1.068 - 1.218）、1.060（0.961 - 1.169）（P = 0.003）。亚组分析显示，在老年女性中，较长的睡眠时间（>8小时）也与心血管代谢疾病的患病率风险增加相关，PR为1.169（1.001 - 1.365）（P = 0.049）。
睡眠时间较短（<6小时）与普通人群中心血管代谢疾病风险增加相关，而睡眠时间较长（>8小时）也会增加老年女性的患病率风险。
