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何时何地:美国县级心脏病死亡率近期增长的时间在地理上的差异。

The where of when: Geographic variation in the timing of recent increases in US county-level heart disease death rates.

机构信息

Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA.

Division for Heart Disease and Stroke Prevention, Centers for Disease Control and Prevention, Atlanta, GA.

出版信息

Ann Epidemiol. 2022 Aug;72:18-24. doi: 10.1016/j.annepidem.2022.05.002. Epub 2022 May 13.

Abstract

PURPOSE

Within the context of local increases in US heart disease death rates, we estimated when increasing heart disease death rates began by county among adults aged 35-64 years and characterized geographic variation.

METHODS

We applied Bayesian spatiotemporal models to vital statistics data to estimate the timing (i.e., the year) of increasing county-level heart disease death rates during 1999-2019 among adults aged 35-64 years. To examine geographic variation, we stratified results by US Census region and urban-rural classification.

RESULTS

The onset of increasing heart disease death rates among adults aged 35-64 years spanned the two-decade study period from 1999 to 2019. Overall, 43.5% (95% CI: 41.3, 45.6) of counties began increasing before 2011, with early increases more prevalent outside of the most urban counties and outside of the Northeast. Roughly one-in-five (18.4% [95% CI: 15.6, 20.7]) counties continued to decline throughout the study period.

CONCLUSIONS

This variation suggests that factors associated with these geographic classifications may be critical in establishing the timing of changing trends in heart disease death rates. These results reinforce the importance of spatiotemporal surveillance in the early identification of adverse trends and in informing opportunities for tailored policies and programs.

摘要

目的

在美国心脏病死亡率局部上升的背景下,我们估计了 35-64 岁成年人中县一级心脏病死亡率上升的开始时间,并描述了其地理差异。

方法

我们应用贝叶斯时空模型对生命统计数据进行分析,以估计 1999 年至 2019 年期间 35-64 岁成年人的县一级心脏病死亡率上升的时间(即年份)。为了研究地理差异,我们根据美国人口普查区域和城乡分类对结果进行分层。

结果

35-64 岁成年人心脏病死亡率上升的起始时间跨越了从 1999 年到 2019 年的二十年研究期。总体而言,43.5%(95%置信区间:41.3,45.6)的县在 2011 年之前就开始出现上升趋势,早期的上升趋势在最城市化的县以及东北部以外的地区更为普遍。大约五分之一(18.4%[95%置信区间:15.6,20.7])的县在整个研究期间持续下降。

结论

这种差异表明,与这些地理分类相关的因素可能在确定心脏病死亡率变化趋势的时间方面至关重要。这些结果强调了时空监测在早期识别不利趋势以及为制定有针对性的政策和计划提供信息方面的重要性。

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