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体重变化对全关节置换术后患者报告结局的影响。

Effect of Weight Change on Patient-Reported Outcomes Following Total Joint Arthroplasty.

机构信息

Anne Arundel Medical Center, Annapolis, Maryland.

出版信息

J Arthroplasty. 2022 Oct;37(10):1991-1997.e1. doi: 10.1016/j.arth.2022.04.029. Epub 2022 May 13.

DOI:10.1016/j.arth.2022.04.029
PMID:35569706
Abstract

BACKGROUND

Increased body mass index (BMI) has been previously described as a risk factor for complications after total joint arthroplasty (TJA); however, its effect on patient-reported outcomes has not been thoroughly investigated. This study examines the effect of postoperative weight change on the Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS-PF) scores for total knee arthroplasty (TKA) and total hip arthroplasty (THA) patients.

METHODS

A retrospective review of 988 patients undergoing THA or TKA was performed. PROMIS-PF scores and BMI were recorded throughout the study duration. Patients were classified by a 5% change in BMI. A univariate analysis evaluated differences across groups. Mixed-effect models evaluated predictors of change in functional score over the postoperative follow-up time.

RESULTS

43.1% patients had a THA and 56.9% patients had a TKA. At 0 to 3 months, 92% of patients had no change in BMI, 3 to 6 months 82% had no change, and 6 to 12 months 80% had no change. There were no significant demographic or comorbidity differences across groups for both THA and TKA. Similar improvements in PROMIS-PF scores were observed across weight change groups. In the mixed-effect models, postoperative time was found to be a significant predictor of postoperative PF score. Both THA and TKA patients saw greater improvements in PROMIS-PF scores in patients with lower preoperative BMIs.

CONCLUSION

These results demonstrate most patients do not experience substantial changes in weight following TJA. However, lower BMIs at the time of surgery were associated with an increased functional improvement. Therefore, efforts to optimize BMI should be focused preoperatively to improve surgical outcomes.

摘要

背景

体重指数(BMI)增加已被先前描述为全关节置换术后并发症的危险因素;然而,其对患者报告的结果的影响尚未得到彻底研究。本研究检查了术后体重变化对全膝关节置换术(TKA)和全髋关节置换术(THA)患者的患者报告的结局测量信息系统身体功能(PROMIS-PF)评分的影响。

方法

对 988 例接受 THA 或 TKA 的患者进行了回顾性研究。在整个研究期间记录了 PROMIS-PF 评分和 BMI。根据 BMI 的 5%变化对患者进行分类。单变量分析评估了组间差异。混合效应模型评估了术后随访时间内功能评分变化的预测因素。

结果

43.1%的患者行 THA,56.9%的患者行 TKA。在 0 至 3 个月时,92%的患者 BMI 无变化,3 至 6 个月时 82%无变化,6 至 12 个月时 80%无变化。THA 和 TKA 两组在人口统计学和合并症方面没有显著差异。在体重变化组中观察到相似的 PROMIS-PF 评分改善。在混合效应模型中,术后时间被发现是术后 PF 评分的一个显著预测因素。THA 和 TKA 患者的 PROMIS-PF 评分在术前 BMI 较低的患者中均有较大改善。

结论

这些结果表明,大多数患者在 TJA 后体重不会发生实质性变化。然而,手术时较低的 BMI 与功能改善增加相关。因此,应在术前集中精力优化 BMI,以改善手术结果。

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