Department of Orthopedic Surgery, NYU Langone Health, 301 East 17 Street 15 Fl Suite 1518, New York, NY, USA.
Arch Orthop Trauma Surg. 2024 Jun;144(6):2889-2898. doi: 10.1007/s00402-024-05381-8. Epub 2024 May 26.
The influence of obesity on patient-reported outcome measures (PROMs) following total hip arthroplasty (THA) is currently controversial. This study aimed to compare PROM scores for pain, functional status, and global physical/mental health based on body mass index (BMI) classification.
Primary, elective THA procedures at a single institution between 2018 and 2021 were retrospectively reviewed, and patients were stratified into four groups based on BMI: normal weight (18.5-24.99 kg/m), overweight (25-29.99 kg/m), obese (30-39.99 kg/m), and morbidly obese (> 40 kg/m). Patient-Reported Outcome Measurement Information System (PROMIS) and Hip Disability and Osteoarthritis Outcome Score for Joint Replacement (HOOS, JR) scores were collected. Preoperative, postoperative, and pre/post- changes (pre/post-Δ) in scores were compared between groups. Multiple linear regression was used to assess for confounders.
We analyzed 3,404 patients undergoing 3,903 THAs, including 919 (23.5%) normal weight, 1,374 (35.2%) overweight, 1,356 (35.2%) obese, and 254 (6.5%) morbidly obese cases. HOOS, JR scores were worse preoperatively and postoperatively for higher BMI classes, however HOOS, JR pre/post-Δ was comparable between groups. All PROMIS measures were worse preoperatively and postoperatively in higher BMI classes, though pre/post-Δ were comparable for all groups. Clinically significant improvements for all BMI classes were observed in all PROM metrics except PROMIS mental health. Regression analysis demonstrated that obesity, but not morbid obesity, was independently associated with greater improvement in HOOS, JR.
Obese patients undergoing THA achieve lower absolute scores for pain, function, and self-perceived health, despite achieving comparable relative improvements in pain and function with surgery. Denying THA based on BMI restricts patients from clinically beneficial improvements comparable to those of non-obese patients, though morbidly obese patients may benefit from additional weight loss to achieve maximal functional improvement.
肥胖对全髋关节置换术(THA)后患者报告的结局测量(PROM)的影响目前存在争议。本研究旨在根据体重指数(BMI)分类比较疼痛、功能状态和整体身体/心理健康的 PROM 评分。
回顾性分析 2018 年至 2021 年在一家机构进行的初次、择期 THA 手术,并根据 BMI 将患者分为四组:正常体重(18.5-24.99 kg/m)、超重(25-29.99 kg/m)、肥胖(30-39.99 kg/m)和病态肥胖(>40 kg/m)。收集患者报告的测量信息系统(PROMIS)和髋关节残疾和骨关节炎结果评分用于关节置换术(HOOS,JR)评分。比较组间评分的术前、术后和术前/术后变化(pre/post-Δ)。采用多元线性回归评估混杂因素。
我们分析了 3404 名接受 3903 例 THA 的患者,包括 919 名(23.5%)正常体重、1374 名(35.2%)超重、1356 名(35.2%)肥胖和 254 名(6.5%)病态肥胖患者。HOOS,JR 评分在较高 BMI 类别中术前和术后较差,但组间 HOOS,JR pre/post-Δ 无差异。所有 PROMIS 测量指标在较高 BMI 类别中术前和术后均较差,但所有组的 pre/post-Δ 无差异。除 PROMIS 心理健康外,所有 BMI 类别均观察到所有 PROM 指标的临床显著改善。回归分析表明,肥胖而不是病态肥胖与 HOOS,JR 更大的改善独立相关。
接受 THA 的肥胖患者在疼痛、功能和自我感知健康方面的绝对评分较低,尽管手术对疼痛和功能的相对改善相当。根据 BMI 拒绝 THA 会限制患者获得与非肥胖患者相当的临床获益改善,尽管病态肥胖患者可能受益于额外的体重减轻以实现最大的功能改善。