Yigit Busra, Oner Can, Cetin Huseyin, Simsek Engin Ersin
Department of Family Medicine, the Health Sciences University Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.
Ann Geriatr Med Res. 2022 Jun;26(2):134-139. doi: 10.4235/agmr.22.0027. Epub 2022 May 16.
Sarcopenia and cognitive disorders are frequently observed in older individuals. This study investigated the relationship between sarcopenia and cognitive function in this population.
This cross-sectional study included 201 participants aged >65 years in Istanbul between July 1, 2020 and January 31, 2021. We screened all participants using the SARC-F (strength, assistance with walking, rising from a chair, climbing stairs, and falls) questionnaire to determine the risk of sarcopenia. Handgrip strength and skeletal muscle mass of participants at risk were measured to diagnose sarcopenia. Sarcopenia severity was evaluated using a 4-m walking speed test. We evaluated the cognitive status of participants using the Standardized Mini-Mental Test (SMMT) and the Standardized Mini-Mental Test for the Untrained (SMMT-E).
It was found that 10.9% (n=22) of participants was risky for sarcopenia and 6.0% (n=12) and 33.3% (n=4) had definite and severe sarcopenia, respectively. Examination of the association between cognitive impairment and SARC-F showed that 8.6% (n=14) of participants with normal cognitive function were at risk of sarcopenia compared to 20.5% (n=8) of participants with cognitive impairment (p=0.045). Evaluation of the relationship between cognitive function and sarcopenia status showed that 3.7% (n=6) of participants with normal cognitive function had sarcopenia compared to 15.4% (n=6) among participants with cognitive impairment (p=0.006).
The rate of sarcopenia was significantly higher in older individuals with cognitive than those with normal cognitive functions.
肌肉减少症和认知障碍在老年人中很常见。本研究调查了该人群中肌肉减少症与认知功能之间的关系。
这项横断面研究纳入了2020年7月1日至2021年1月31日期间在伊斯坦布尔年龄大于65岁的201名参与者。我们使用SARC - F（力量、行走辅助、从椅子上起身、爬楼梯和跌倒）问卷对所有参与者进行筛查，以确定肌肉减少症的风险。对有风险的参与者测量握力和骨骼肌质量以诊断肌肉减少症。使用4米步行速度测试评估肌肉减少症的严重程度。我们使用标准化简易精神状态检查（SMMT）和非训练者标准化简易精神状态检查（SMMT - E）评估参与者的认知状态。
发现10.9%（n = 22）的参与者有肌肉减少症风险，6.0%（n = 12）和33.3%（n = 4）的参与者分别患有明确的和严重的肌肉减少症。对认知障碍与SARC - F之间关联的检查显示，认知功能正常的参与者中有8.6%（n = 14）有肌肉减少症风险，而认知障碍参与者中有20.5%（n = 8）有该风险（p = 0.045）。对认知功能与肌肉减少症状态之间关系的评估显示，认知功能正常的参与者中有3.7%（n = 6）患有肌肉减少症，而认知障碍参与者中有15.4%（n = 6）患有该疾病（p = 0.006）。
认知功能受损的老年人中肌肉减少症的发生率显著高于认知功能正常的老年人。
