Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Vaccination Unit, ASST Fatebenefratelli Sacco, 20157 Milan, Italy.
Vaccine. 2022 Jun 9;40(26):3664-3669. doi: 10.1016/j.vaccine.2022.05.005. Epub 2022 May 13.
COVID-19 has led to disruption in routine immunization programs around the world. Effective strategies need to be developed to address the decline in vaccine coverage to avoid preventable disease outbreaks. Our study reports a 4-days campaign for the catching-up of missed vaccinations in children aged between 6 and 8 years, in Milan, Italy.
The catch-up vaccination campaign (21st-24th of September 2021) involved children born in 2013, 2014 and 2015. These cohorts, if not already immunized, received the fourth dose of the Diphtheria-Tetanus-acellular Pertussis and Poliomyelitis vaccination (DTaPP4), the second dose of the Measles-Mumps and Rubella vaccination (MMR2) and Chickenpox, according to the Italian vaccine schedule.
3,943 letters were sent to children with a missing vaccination. 1,315 children, 33% of expected, were vaccinated during the campaign. The 2015 cohort was the one that benefited most from the initiative, 955 children were vaccinated for a total of 1,864 doses administered. This has led to a significant increase of 20.0 percentage points (p.p.) in vaccination coverages for the fourth dose of DTaPP and the second dose of MMR. 214 children for the 2014 cohort and 146 for the 2013 cohort were vaccinated during the following days, these cohorts have been already called previously therefore the participation in the campaign and consequently the increase in vaccination coverages were less substantial.
This experience has demonstrated that a mass vaccination campaign could be a useful tool in catch-up strategies, even during the pandemic. It should be part of a bigger immunization program strategy that also includes efforts to simultaneously strengthen routine immunization services. With the appropriate organizational improvements, this initiative could pave the way for future successful campaigns involving different age groups and vaccinations.
COVID-19 导致全球常规免疫规划中断。需要制定有效的策略来应对疫苗接种率下降,以避免可预防的疾病爆发。本研究报告了在意大利米兰针对 6 至 8 岁儿童错过疫苗接种的 4 天补种活动。
补种疫苗活动(2021 年 9 月 21 日至 24 日)涉及 2013 年、2014 年和 2015 年出生的儿童。如果这些儿童尚未免疫,将根据意大利疫苗接种计划接种第四剂白喉、破伤风、无细胞百日咳和脊髓灰质炎疫苗(DTaPP4)、第二剂麻疹、腮腺炎和风疹疫苗(MMR2)和水痘疫苗。
共向 3943 名未接种疫苗的儿童发送了信函。33%(1315 名)预期的儿童在活动期间接种了疫苗。2015 年出生的儿童受益最多,共有 955 名儿童接种了 1864 剂疫苗。这导致 DTaPP 第四剂和 MMR 第二剂疫苗接种覆盖率显著提高了 20.0 个百分点(p.p.)。2014 年出生的儿童中有 214 名和 2013 年出生的儿童中有 146 名在随后的几天接种了疫苗,这些儿童之前已经被召集过,因此他们参与活动和疫苗接种覆盖率的增加就不太显著。
这一经验表明,大规模疫苗接种活动可能是追赶战略中的一种有用工具,即使在大流行期间也是如此。它应该成为更大免疫规划战略的一部分,该战略还包括努力同时加强常规免疫服务。通过适当的组织改进,这一倡议可以为未来涉及不同年龄组和疫苗接种的成功活动铺平道路。