Department of Burn and Plastic Surgery, The General Hospital of Western Theater Command, Chengdu, China.
Department of General Medicine, The General Hospital of Western Theater Command, Chengdu, China.
Front Public Health. 2022 Apr 29;10:808873. doi: 10.3389/fpubh.2022.808873. eCollection 2022.
The outbreak of coronavirus disease 2019 (COVID-19) has endangered human health and life. This pandemic has changed people's lifestyle and affected the regular delivery of standard cancer treatment. In the present study, we aimed to explore the influencing factors of delayed treatment in patients with breast cancer during COVID-19 pandemic.
This study was a cross-sectional investigation, and the subjects were patients who were discharged from the department of burn and plastic surgery after February 2020. All participants completed this study's online questionnaire based on the WeChat and Wenjuanxing platforms. Levels of anxiety and depression were measured by the Hospital Anxiety and Depression Scale (HADS). Patients were divided into a delay group and non-delay group according to the occurrence of delayed treatment. Univariate analysis was performed by using the test or chi-square test. A logistic regression model was employed to determine factors associated with delayed treatment.
The present study included a total of 397 patients with breast cancer, among whom delayed treatment occurred in 76 patients, accounting for 19.1%. Scores on both the anxiety subscale and depression subscale in delay group were significantly higher than those in non-delay group. Compared with non-delay group, we found that patients in delay group usually had a higher level of education ( = 0.020), worse self-feeling ( = 0.030), poor compliance of medical order ( = 0.042), and a higher prevalence of anxiety ( = 0.004) and depression ( = 0.012). Traffic inconvenience was also an important relevant factor for delayed treatment ( = 0.001). The prevalence of recurrence in delay group was higher than that in non-delay group ( = 0.018). By using logistic multivariate regression analysis, the results revealed that level of education and traffic inconvenience were independent factors influencing delayed treatment in patients with breast cancer during COVID-19 pandemic.
The prevalence of delayed treatment in patients with breast cancer during COVID-19 pandemic is relatively high. Our findings reveal several influencing factors closely associated with delayed treatment, which is useful information that will be beneficial for patients to receive standardized therapy by taking targeted measures.
2019 年冠状病毒病（COVID-19）的爆发危及人类健康和生命。这场大流行改变了人们的生活方式，并影响了标准癌症治疗的正常进行。在本研究中，我们旨在探讨 COVID-19 大流行期间乳腺癌患者延迟治疗的影响因素。
本研究为横断面调查，研究对象为 2020 年 2 月后从烧伤整形外科出院的患者。所有参与者均基于微信和问卷星平台完成本研究的在线问卷。采用医院焦虑抑郁量表（HADS）评估焦虑和抑郁水平。根据是否发生延迟治疗，将患者分为延迟组和非延迟组。采用卡方检验或 Fisher 确切概率法进行单因素分析，采用二分类 Logistic 回归模型确定与延迟治疗相关的因素。
本研究共纳入 397 例乳腺癌患者，其中 76 例发生延迟治疗，占 19.1%。延迟组焦虑和抑郁亚量表评分均明显高于非延迟组。与非延迟组相比，延迟组患者的文化程度较高（ = 0.020）、自我感觉较差（ = 0.030）、医嘱执行较差（ = 0.042）、焦虑和抑郁的发生率较高（ = 0.004， = 0.012）。交通不便也是导致延迟治疗的重要相关因素（ = 0.001）。延迟组的复发率高于非延迟组（ = 0.018）。多因素 logistic 回归分析结果显示，文化程度和交通不便均是 COVID-19 大流行期间乳腺癌患者延迟治疗的独立影响因素。
COVID-19 大流行期间乳腺癌患者延迟治疗的发生率相对较高。本研究发现了与延迟治疗密切相关的几个影响因素，这为患者通过采取针对性措施接受标准化治疗提供了有益的信息。
